5-HT2A Products
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
65 results for "5-HT2A" in Products
65 results for "5-HT2A" in Products
5-HT2A Products
5-HT2A encodes one of the receptors for serotonin, a neurotransmitter with many roles. Mutations in 5-HT2A are associated with susceptibility to schizophrenia and obsessive-compulsive disorder, and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD). MDD patients who also have a mutation in intron 2 of 5-HT2A show a significantly reduced response to citalopram as this antidepressant downregulates expression of this gene.
Endogenous 5-HT receptor agonist
| Alternate Names: | 5-Hydroxytryptamine,5-HT |
| Chemical Name: | 3-(2-Aminoethyl)-1H-indol-5-ol hydrochloride |
| Purity: | ≥98% (HPLC) |
Dopamine antagonist with some D4 selectivity; also 5-HT2A/2C antagonist
| Chemical Name: | 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine |
| Purity: | ≥99% (HPLC) |
Potent and selective 5-HT2A antagonist
| Alternate Names: | Volinanserin |
| Chemical Name: | (R)-(+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperinemethanol |
| Purity: | ≥98% (HPLC) |
| Details: | Mouse IgG1 Monoclonal Clone #1055217 |
| Applications: | WB, Flow, ICC |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1055220 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1055220 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1055220 |
| Applications: | Flow, ICC |
High affinity and potent 5-HT2A agonist
| Chemical Name: | (4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylamine hydrobromide |
| Purity: | ≥99% |
Selective 5-HT2A antagonist
| Chemical Name: | 7-[[4-[2-(4-Fluorophenyl)ethyl]-1-piperazinyl]carbonyl]-1H-indole-3-carbonitrile hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective 5-HT2A antagonist. Also antagonist at 5-HT1D
| Alternate Names: | R 41 468 |
| Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,4[1H,3H]-quinazolinedione tartrate |
| Purity: | ≥97% (HPLC) |
Potent, selective 5-HT2A antagonist
| Chemical Name: | (2R,4R)-5-[2-[2-[2-(3-Methoxyphenyl)ethyl]phenoxy]ethyl]-1-methyl-3-pyrrolidinol hydrochloride |
| Purity: | ≥99% |
High affinity D2 and 5-HT1A receptor partial agonist; also 5-HT2A antagonist
| Chemical Name: | 7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-3,4-dihydro-2(1H)-quinolinone |
| Purity: | ≥99% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1055220 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #1055220 |
| Applications: | Flow |
Selective 5-HT2A antagonist
| Chemical Name: | 4-(4-Fluorobenzoyl)-1-(4-phenylbutyl)piperidine oxalate |
| Purity: | ≥99% (HPLC) |
5-HT2A antagonist
| Chemical Name: | α-Phenyl-1-(2-phenylethyl)-4-piperidinemethanol |
| Purity: | ≥99% (HPLC) |
High affinity and selective 5-HT2A agonist
| Chemical Name: | 4-[2-[[(2-Hydroxyphenyl)methyl]amino]ethyl]-2,5-dimethoxybenzonitrile hydrochloride |
| Purity: | ≥98% |
Selective 5-HT2A inverse agonist
| Chemical Name: | N-[(4-Fluorophenyl)methyl]-N-(1-methyl-4-piperidinyl)-N'-[[4-(2-methylpropoxy)phenyl]methyl]urea |
| Purity: | ≥98% |
5-HT2 antagonist; also D2 antagonist; atypical antipsychotic
| Chemical Name: | 2-[2-(4-Dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazinyl)ethoxy]ethanol hemifumarate |
| Purity: | ≥99% |
D2-like agonist (D2>D3>D4)
| Chemical Name: | (5'a)-2-Bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)ergotaman-3',6',18-trione mesylate |
| Purity: | ≥98% (HPLC) |
5-HT2A and 5-HT2C antagonist; also D2-like partial agonist
| Alternate Names: | CU-32-085 |
| Chemical Name: | N'-[(8-α1,6-dimethylergolin-8-yl]-N,N-dimethylsulfamide hydrochloride |
| Purity: | ≥99% (HPLC) |
Potent and selective 5-HT2A antagonist
| Alternate Names: | SR-46349 hemifumarate,SR-46349B |
| Chemical Name: | (1Z,2E)-1-(2-Fluorophenyl)-3-(4-hydroxyphenyl)-2-propen-1-one O-[2-(dimethylamino)ethyl]oxime hemifumarate |
| Purity: | ≥98% (HPLC) |
5-HT2A antagonist; also D2 antagonist; atypical antipsychotic
| Alternate Names: | 9-Hydroxyrisperidone,9-OH-risperidone |
| Chemical Name: | 3-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-9-hydroxy-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
5-HT2A receptor antagonist
| Chemical Name: | 3-[2-[4-(4-Fluorobenzoyl)-1-piperidinyl]ethyl]-2,3-dihydro-2-thioxo-4(1H)-quinazolinone hydrochloride |
| Purity: | ≥98% (HPLC) |
