Skip to main content

A-Raf Products

The Raf serine/threonine kinases are effectors of Ras that function as MAP3Ks in the ERK phosphorylation cascade. Mammals express three Raf proteins: A-Raf, B-Raf, and Raf-1, also known as C-Raf. Human A-Raf is a 70 kDa protein that shares three regions with B-Raf and Raf-1: aa 14-153 which contains a Ras-binding domain, a Cys-rich domain, and a lipid-binding domain; aa 209-223; and aa 308-573 which contains the Ser/Thr protein kinase domain and a second lipid-binding domain. A-Raf is activated by phosphorylation at Ser 257, 262, and 264. It then regulates multiple processes including endocytic trafficking, glycolysis, cell cycle progression, and apoptosis.

Show More

47 results for "A-Raf" in Products

47 results for "A-Raf" in Products

A-Raf Products

The Raf serine/threonine kinases are effectors of Ras that function as MAP3Ks in the ERK phosphorylation cascade. Mammals express three Raf proteins: A-Raf, B-Raf, and Raf-1, also known as C-Raf. Human A-Raf is a 70 kDa protein that shares three regions with B-Raf and Raf-1: aa 14-153 which contains a Ras-binding domain, a Cys-rich domain, and a lipid-binding domain; aa 209-223; and aa 308-573 which contains the Ser/Thr protein kinase domain and a second lipid-binding domain. A-Raf is activated by phosphorylation at Ser 257, 262, and 264. It then regulates multiple processes including endocytic trafficking, glycolysis, cell cycle progression, and apoptosis.

Show More
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse
Applications: WB
Reactivity: Human
Applications: WB, ELISA, MA, AP, Enzyme Activity
Applications: WB, ELISA, Func
Reactivity: Human
Applications: WB, ELISA, MA, AP
Catalog #: H00000369-Q02
Applications: WB, ELISA, MA, AP
Applications: IHC, WB
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human
Applications: IHC, WB
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB
Reactivity: Human, Mouse, Rat
Catalog #: H00000369-Q01
Applications: WB, ELISA, MA, AP
Applications: AC
Applications: AC
Applications: WB
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Applications: IHC, WB
Reactivity: Human, Mouse, Rat
Results Per Page
5 10 25 50
/ 2