AIF Products
Apoptosis-inducing factor (AIF) is a 57-kDa flavoprotein, with orthology to bacterial oxidoreductases, that is localized to the mitochondria. Mitochondria play a key role in the regulation of apoptosis. AIF is released into the cytosol, translocated to the nucleus, and initiates chromatin condensation as part of the intrinsic Caspase-9-mediated apoptosis pathway. Some mitochondrial-regulated apoptotic pathways are Caspase-independent. AIF may play a role in this type of programmed cell death.
2 results for "AIF" in Products
2 results for "AIF" in Products
AIF Products
Apoptosis-inducing factor (AIF) is a 57-kDa flavoprotein, with orthology to bacterial oxidoreductases, that is localized to the mitochondria. Mitochondria play a key role in the regulation of apoptosis. AIF is released into the cytosol, translocated to the nucleus, and initiates chromatin condensation as part of the intrinsic Caspase-9-mediated apoptosis pathway. Some mitochondrial-regulated apoptotic pathways are Caspase-independent. AIF may play a role in this type of programmed cell death.
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, KO |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | ICC |
