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Apoptosis Inducer Compounds Products

Apoptosis inducers produce pro-apoptotic effects via different mechanisms. These include DNA cross-linking, inhibition of antiapoptotic proteins, and activation of caspases. These apoptosis inducers can target specific cellular processes to induce antitumor or antineoplastic effects.

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29 results for "Apoptosis Inducer Compounds" in Products

29 results for "Apoptosis Inducer Compounds" in Products

Apoptosis Inducer Compounds Products

Apoptosis inducers produce pro-apoptotic effects via different mechanisms. These include DNA cross-linking, inhibition of antiapoptotic proteins, and activation of caspases. These apoptosis inducers can target specific cellular processes to induce antitumor or antineoplastic effects.

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Promotes apoptosome formation and activates caspase-9/caspase-3 pathway. Selectively induces tumor cell apoptosis

Potent pro-apoptotic anticancer agent; activates caspase-3

Antitumor antibiotic agent. Inhibits DNA topoisomerase II

DNA cross-linking antitumor agent

Alkylating agent; chemotherapeutic

DNA cross-linking antitumor agent

Inhibits RNA polymerase

DNA-methylating antitumor agent

Potent and selective Bcl-xL inhibitor; antitumor and inducer of apoptosis

DNA cross-linking antitumor agent

Potent and selective MEK inhibitor; orally bioavailable

Antitumor and anti-HIV agent; activates NF-κB. Also TGR5 agonist

Proapoptotic; downregulates PLK1 expression and activates mitochondrial Ca2+ uniporter

Bcl-2 family inhibitor; mimics BH3 and induces apoptosis in cancer cell lines

DNA alkylator; antitumor and induces diabetes

Applications: AdAct

Hypoxia-activated DNA alkylating agent prodrug

Inhibits RNAPII-mediated transcription; antitumor, anti-inflammatory and immunosuppressive

Purine analog; inhibits DNA synthesis

Downregulates Bcl-2 and Mcl-1; pro-apoptotic

Thymidine analog for labeling DNA; can be linked to a fluorophore by click chemistry

High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Potent fatty acid synthase inhibitor; proapoptotic

Stimulates RhoA activation; antiproliferative agent that slows cell cycle progression

High affinity and selective activator of Bax

Potent pan-HDAC inhibitor

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