BACE-1 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
1 result for "BACE-1" in Products
1 result for "BACE-1" in Products
BACE-1 Products
Both BACE-1 and BACE-2 are membrane-bound aspartic proteases of the pepsin family. BACE-1 is a potential target for treatment of Alzheimer's disease because it is the principle b-secretase responsible for cleavage of amyloid precursor protein (APP). BACE-2 differs from BACE-1 in several aspects including pro-enzyme activation, substrate binding sites, transcriptional regulation, and function in A beta peptide production.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #137626 |
| Applications: | IP, Neut |
