beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
519 results for "beta-Catenin" in Products
519 results for "beta-Catenin" in Products
beta-Catenin Products
beta-Catenin, also known as CTNNB1, is a cadherin-associated protein that is involved in the regulation of cell adhesion. This multifunctional protein is also implicated in the canonical Wnt signal transduction pathway, acting as a transcriptional co-activator. Nuclear beta-Catenin activates the TCF/LEF family of transcription factors, inducing the transcription of pro-mitotic genes.
Contains 4 sets of 2 membranes - each spotted in duplicate with antibodies against 37 different kinases and 2 related total proteins
Potent tankyrase inhibitor
| Alternate Names: | XAV939 Wnt Signaling Inhibitor |
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, IHC, ChIP, CyTOF-ready, +2 More |
| Reactivity: | Human, Mouse, Rat, Primate, Chicken, +3 More |
| Details: | Mouse IgG1 Monoclonal Clone #12F7 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
![Western Blot: beta-Catenin Antibody (12F7)BSA Free [NBP1-54467]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-12F7-Western-Blot-NBP1-54467-img0008.jpg "Western Blot: beta-Catenin Antibody (12F7)BSA Free [NBP1-54467]")
Potent inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-3-(2-methoxyphenyl)-4-oxothieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #196621 |
| Applications: | WB, IHC, mIF |
Wnt/β-catenin signaling inhibitor; axin stabilizer
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Canine, Zebrafish, +2 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +2 More |
![Western Blot: beta-Catenin Antibody [NBP1-32239]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-Western-Blot-NBP1-32239-img0033.jpg "Western Blot: beta-Catenin Antibody [NBP1-32239]")
Inhibits TCF/β-catenin-mediated transcription
| Chemical Name: | (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA |
![Western Blot: beta-Catenin [p Ser45] AntibodyAzide and BSA Free [NBP3-05442]](https://resources.bio-techne.com/images/products/beta-Catenin-[p-Ser45]-Antibody-Western-Blot-NBP3-05442-img0001.jpg "Western Blot: beta-Catenin [p Ser45] AntibodyAzide and BSA Free [NBP3-05442]")
| Reactivity: | Human |
| Details: | Mouse IgG3 Monoclonal Clone #196618 |
| Applications: | WB, IHC, ICC |
| Applications: | Bioactivity, PAGE |
| Assay Range: | 312 - 20,000 pg/mL |
| Applications: | ELISA |
Wnt signaling inhibitor; inhibits β-catenin-transcription factor interactions
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | WB, CyTOF-ready, ICFlow |
| Reactivity: | Human, Mouse, Rat, Fish |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Immunohistochemistry-Paraffin: beta-Catenin Antibody [NBP1-89989]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-Immunohistochemistry-Paraffin-NBP1-89989-img0025.jpg "Immunohistochemistry-Paraffin: beta-Catenin Antibody [NBP1-89989]")
Inhibitor of Wnt/β-catenin signaling
| Chemical Name: | N-[4-(4-Ethyl-1-piperazinyl)phenyl]-2-oxo-2H-1-benzopyran-3-carboxamide |
| Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6A3P2 |
| Applications: | IHC, WB, ICC/IF, IP, KO |
![Western Blot: beta-Catenin Antibody (6A3P2) [NBP3-15842]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-9L6X0-Western-Blot-NBP3-15842-img0008.jpg "Western Blot: beta-Catenin Antibody (6A3P2) [NBP3-15842]")
XAV 939 synthesized to cGMP guidelines
| Chemical Name: | 3,5,7,8-Tetrahydro-2-[4-(trifluoromethyl)phenyl]-4H-thiopyrano[4,3-d]pyrimidin-4-one |
| Purity: | ≥99% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #CTNNB1/1509 |
| Applications: | IHC, WB |
![Western Blot: beta-Catenin Antibody (CTNNB1/1509) [NBP2-53366]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-CTNNB1-1509-Western-Blot-NBP2-53366-img0005.jpg "Western Blot: beta-Catenin Antibody (CTNNB1/1509) [NBP2-53366]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #196624 |
| Applications: | ICFlow |
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SA30-04 |
| Applications: | IHC, WB, ICC/IF, IP, Func |
![Western Blot: beta-Catenin Antibody (SA30-04) [NBP2-67307]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-SA30-04-Western-Blot-NBP2-67307-img0009.jpg "Western Blot: beta-Catenin Antibody (SA30-04) [NBP2-67307]")
Selective peptide-based β-catenin Degrader (PROTAC®)
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human, Mouse, Rat, Monkey, Primate |
| Details: | Mouse IgG1 Monoclonal Clone #OTI12H7 |
| Applications: | IHC, WB, ICC/IF, Flow |
![Western Blot: beta-Catenin Antibody (OTI12H7) [NBP2-03615]](https://resources.bio-techne.com/images/products/beta-Catenin-Antibody-12H7-Western-Blot-NBP2-03615-img0024.jpg "Western Blot: beta-Catenin Antibody (OTI12H7) [NBP2-03615]")
endo-IWR 1 synthesized to Ancillary Material Grade
| Chemical Name: | rel-4-[(3aR,4S,7R,7aS)-1,3,3a,4,7,7a-Hexahydro-1,3-dioxo-4,7-methano-2H-isoindol-2-yl]-N-8-quinolinylbenzamide |
| Purity: | ≥98% |
