Cannabinoid R2 / CB2 Inverse Agonists: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion - except for their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2.
4 results for "Cannabinoid R2 / CB2 Inverse Agonists Small Molecules and Peptides" in Products
4 results for "Cannabinoid R2 / CB2 Inverse Agonists Small Molecules and Peptides" in Products
Cannabinoid R2 / CB2 Inverse Agonists: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion - except for their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2.
Selective CB2 inverse agonist
| Chemical Name: | 6-Iodo-2-methyl-1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl](4-methoxyphenyl)methanone |
| Purity: | ≥98% (HPLC) |
CB2 receptor inverse agonist
| Chemical Name: | N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide |
| Purity: | ≥99% (HPLC) |
Selective CB2 receptor inverse agonist
| Chemical Name: | N-(1,3-Benzodioxol-5-ylmethyl)-1,2-dihydro-7-methoxy-2-oxo-8-(pentyloxy)-3-quinolinecarboxamide |
| Purity: | ≥99% (HPLC) |
Highly potent and selective CB2 inverse agonist
| Chemical Name: | N-[(1S)-1-[4-[[4-Methoxy-2-[(4-methoxyphenyl)sulfonyl]phenyl]sulfonyl]phenyl]ethyl]methanesulfonamide |
| Purity: | ≥98% (HPLC) |
