Cannabinoid R2/CB2 Receptor Ligands: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
1 result for "Cannabinoid R2/CB2 Receptor Ligands Small Molecules and Peptides" in Products
1 result for "Cannabinoid R2/CB2 Receptor Ligands Small Molecules and Peptides" in Products
Cannabinoid R2/CB2 Receptor Ligands: Small Molecules and Peptides
CB2 R is a 7TM protein that belongs to the family of G protein-coupled receptors, class A. CB2 R is expressed in the periphery, notably by hematopoietic cells, in contrast to CB1 R, which is expressed predominantly in the central nervous system and gut. CB2 R on lymphocytes and macrophages binds cannabinoids and modulates cytokine secretion. With the exception of their divergent C-terminal tails, human CB2 R shares 82% amino acid sequence identity with mouse and rat CB2 R.
Positive allosteric modulator of CB2 receptors; active in vivo
| Chemical Name: | N-[5-Bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]cycloheptanecarboxamide |
| Purity: | ≥98% (HPLC) |
