Caspase-8 Products
Caspase-8, also known as MCH5, FLICA and MACH alpha 1, is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 acts on a wide variety of substrates including Pro-Caspases-3, -4, -6, -7, -9 and -10, c-FLIPL and Pro-Caspase‑8 itself. Caspase-8 is recruited to the death-inducing signaling complex (DISC) that forms around the death domains of the oligomerized receptors. Multiple rounds of cleavage generate Caspase-8 p10 and p18 which heterodimerize and then associate into the active tetrameric enzyme containing two p10 and two p18 subunits.
Products:
156 results for "Caspase-8" in Products
156 results for "Caspase-8" in Products
Caspase-8 Products
Caspase-8, also known as MCH5, FLICA and MACH alpha 1, is a 28 kDa member of the peptidase C14A family of enzymes. It is widely expressed and is considered an initiating caspase for the apoptotic cascade. Caspase-8 acts on a wide variety of substrates including Pro-Caspases-3, -4, -6, -7, -9 and -10, c-FLIPL and Pro-Caspase‑8 itself. Caspase-8 is recruited to the death-inducing signaling complex (DISC) that forms around the death domains of the oligomerized receptors. Multiple rounds of cleavage generate Caspase-8 p10 and p18 which heterodimerize and then associate into the active tetrameric enzyme containing two p10 and two p18 subunits.
Products:
| Reactivity: | Human, Mouse, Rat, Gerbil |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +1 More |
![Immunohistochemistry: Caspase-8 Antibody [NB100-56116]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-active-cleaved-Immunohistochemistry-NB100-56116-img0009.jpg "Immunohistochemistry: Caspase-8 Antibody [NB100-56116]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, Simple Western |
| Reactivity: | Human, Primate, Primate - Macaca mulatta (Rhesus Macaque), Insect - Drosophila melanogaster |
| Details: | Mouse IgG1 Monoclonal Clone #90A992 |
| Applications: | IHC, WB, Flow, CyTOF-ready, Simple Western |
![Western Blot: Caspase-8 Antibody (90A992)BSA Free [NB100-56527]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-90A992-Western-Blot-NB100-56527-img0018.jpg "Western Blot: Caspase-8 Antibody (90A992)BSA Free [NB100-56527]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, IP |
![Western Blot: Caspase-8 Antibody(Pro and Active) [NBP1-05123]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Pro-and-Active-Western-Blot-NBP1-05123-img0006.jpg "Western Blot: Caspase-8 Antibody(Pro and Active) [NBP1-05123]")
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Simple Western, KO |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #84131 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG1 kappa Monoclonal Clone #3B10 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow |
![Western Blot: Caspase-8 Antibody (3B10)BSA Free [NBP2-80098]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-3B10-BSA-Free-Western-Blot-NBP2-80098-img0004.jpg "Western Blot: Caspase-8 Antibody (3B10)BSA Free [NBP2-80098]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, KO |
![Knockout Validated: Caspase-8 Antibody [NBP2-15722]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Western-Blot-NBP2-15722-img0005.jpg "Knockout Validated: Caspase-8 Antibody [NBP2-15722]")
| Source: | E. coli |
| Accession #: | Q14790 |
| Applications: | EnzAct |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Caspase-8 AntibodyBSA Free [NBP1-76610]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Western-Blot-NBP1-76610-img0006.jpg "Western Blot: Caspase-8 AntibodyBSA Free [NBP1-76610]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #746109 |
| Applications: | ICC |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #FLICE 4-1-20 |
| Applications: | WB |
![Western Blot: Caspase-8 Antibody (FLICE 4-1-20) [NB500-208]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-FLICE-4-1-20-Western-Blot-NB500-208-img0004.jpg "Western Blot: Caspase-8 Antibody (FLICE 4-1-20) [NB500-208]")
| Reactivity: | Mouse |
| Details: | Rat IgG1 kappa Monoclonal Clone #1G12 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: Caspase-8 Antibody (1G12)BSA Free [NBP2-80097]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-1G12-BSA-Free-Western-Blot-NBP2-80097-img0004.jpg "Western Blot: Caspase-8 Antibody (1G12)BSA Free [NBP2-80097]")
| Reactivity: | Human, Mouse, Rat, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #1H11 |
| Applications: | IHC, WB, ELISA, Flow |
![Western Blot: Caspase-8 Antibody (1H11)BSA Free [NBP2-22183]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-1H11-Western-Blot-NBP2-22183-img0005.jpg "Western Blot: Caspase-8 Antibody (1H11)BSA Free [NBP2-22183]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #PSH04-77 |
| Applications: | IHC, WB, ICC/IF, Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: Caspase-8 Antibody [NBP1-88185]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Western-Blot-NBP1-88185-img0006.jpg "Western Blot: Caspase-8 Antibody [NBP1-88185]")
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Immunohistochemistry-Paraffin: Caspase-8 Antibody [NB600-576]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Immunohistochemistry-Paraffin-NB600-576-img0002.jpg "Immunohistochemistry-Paraffin: Caspase-8 Antibody [NB600-576]")
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: Caspase-8 Antibody [NBP1-88184]](https://resources.bio-techne.com/images/products/Caspase-8-Antibody-Western-Blot-NBP1-88184-img0005.jpg "Western Blot: Caspase-8 Antibody [NBP1-88184]")
| Applications: | ELISA |
![ELISA: Human Caspase-8 ELISA Kit (Colorimetric) [NBP1-83733]](https://resources.bio-techne.com/images/products/Caspase-8-ELISA-Kit-ELISA-NBP1-83733-img0001.jpg "ELISA: Human Caspase-8 ELISA Kit (Colorimetric) [NBP1-83733]")
| Applications: | AC |
| Applications: | AC |