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Cbl-c Products

Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known
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149 results for "Cbl-c" in Products

149 results for "Cbl-c" in Products

Cbl-c Products

Cbl-c is also known as signal transduction protein CBL-C, SH3-binding protein CBL-C, CBL-3, and RING finger protein 57. Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl-c (a.k.a. Cbl-3) is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Cbl-c knock out mice show no obvious phenotype. Thus, the physiological role of Cbl-c is not known
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Applications: IHC, WB, ELISA, IP
Reactivity: Human
Applications: WB, Flow
Reactivity: Human
Applications: WB, Flow
Reactivity: Human
Applications: WB, ELISA
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, ELISA, MA, AP
Applications: WB
Applications: ICC/IF
Reactivity: Human
Applications: WB, IP
Reactivity: Human, Mouse
Applications: WB, ELISA
Reactivity: Human, Mouse
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: WB, Flow, CyTOF-ready
Reactivity: Human
Applications: AC
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
Applications: ELISA
Reactivity: Human
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