CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
103 results for "CD40/TNFRSF5" in Products
103 results for "CD40/TNFRSF5" in Products
CD40/TNFRSF5 Products
CD40, also known as TNFRSF5, is a transmembrane TNF superfamily receptor that is expressed on the surface of B cells, dendritic cells, macrophages, monocytes and platelets, as well as endothelial and epithelial cells. Interaction of CD40 with CD40 Ligand leads to the aggregation of CD40 molecules resulting in the initiation of bidirectional intracellular signaling in both CD40 and CD40 Ligand expressing cells. This interaction promotes B cell activation and T cell-dependent humoral responses. CD40 serves multiple functions in both hematopoietic and epithelial cancers and is a target for tumor immunotherapy. Dysregulation of CD40/CD40 Ligand expression and interactions contributes to disease severity in AIDS, atherosclerosis, atherothrombosis, and restenosis.
Clone G28-5 was used by HLDA to establish CD designation.
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #G28-5 |
Applications: | IHC, ICC/IF, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #G28.5 |
Applications: | IHC, Flow, IP, CyTOF-ready, Func |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #C40/1605 |
Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #C40/1605 |
Applications: | IHC, ICC/IF, Flow, CyTOF-ready |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #G28.5 |
Applications: | IHC, Flow, IP, CyTOF-ready, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #G28.5 |
Applications: | IHC, Flow, IP, CyTOF-ready, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG1 kappa Monoclonal Clone #C40/9225R |
Applications: | IHC |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |
Clone 5C3 was used by HLDA to establish CD designation.
Reactivity: | Human, Mouse |
Details: | Mouse IgG1 kappa Monoclonal Clone #5C3 |
Applications: | IHC, ICC/IF, Flow |