CEACAM-1/CD66a: Lysates
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic regions. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.
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1 result for "CEACAM-1/CD66a Lysates" in Products
1 result for "CEACAM-1/CD66a Lysates" in Products
CEACAM-1/CD66a: Lysates
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic regions. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.
Products:
| Applications: | WB |
![Western Blot: CEACAM1/CD66a Overexpression Lysate [NBP2-10255]](https://resources.bio-techne.com/images/products/CEACAM1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-10255-img0001.jpg "Western Blot: CEACAM1/CD66a Overexpression Lysate [NBP2-10255]")