Clusterin Products
Clusterin, also known as Apolipoprotein J, Sulfated Glycoprotein 2 (SGP-2), TRPM-2, and SP-40,40, is a secreted multifunctional protein that binds a wide range of molecules and may function as a chaperone of misfolded extracellular proteins. It also participates in the control of cell proliferation, apoptosis, and carcinogenesis. Clusterin is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. It is secreted as a disulfide-linked heterodimer of alpha and beta chains and circulates as a component of high density lipoprotein (HDL) particles. Clusterin exerts tissue protective functions in atherosclerosis and Alzheimer’s disease by binding and neutralizing non-oxidatively modified LDL reduces cytotoxicity and beta-amyloid fibrils, respectively. Increased circulating levels of Clusterin enhance tumor aggressiveness by inhibiting apoptosis and by promoting epithelial to mesenchymal transition.
189 results for "Clusterin" in Products
189 results for "Clusterin" in Products
Clusterin Products
Clusterin, also known as Apolipoprotein J, Sulfated Glycoprotein 2 (SGP-2), TRPM-2, and SP-40,40, is a secreted multifunctional protein that binds a wide range of molecules and may function as a chaperone of misfolded extracellular proteins. It also participates in the control of cell proliferation, apoptosis, and carcinogenesis. Clusterin is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. It is secreted as a disulfide-linked heterodimer of alpha and beta chains and circulates as a component of high density lipoprotein (HDL) particles. Clusterin exerts tissue protective functions in atherosclerosis and Alzheimer’s disease by binding and neutralizing non-oxidatively modified LDL reduces cytotoxicity and beta-amyloid fibrils, respectively. Increased circulating levels of Clusterin enhance tumor aggressiveness by inhibiting apoptosis and by promoting epithelial to mesenchymal transition.
Source: | NS0 |
Accession #: | NP_001822 |
Applications: | BA |
Sensitivity: | 1.05 ng/mL |
Applications: | ELISA |
Assay Range: | 3.12 - 200 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Urine) |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, IP |
Simple Plex Human Clusterin assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
Sensitivity: | 0.094 ng/mL |
Applications: | ELISA |
Assay Range: | 0.781 - 50 ng/mL (Cell Culture Supernates, Cell Lysates, Serum, EDTA Plasma, Heparin Plasma, Urine) |
Control for use with Human Clusterin Simple Plex Cartridge Kit
Applications: | Ctrl, Simple Plex |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC, IP |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #350227 |
Applications: | WB, IHC, IP |
Assay Range: | 62.5 - 4,000 pg/mL |
Applications: | ELISA |
Source: | NS0 |
Accession #: | Q06890 |
Applications: | BA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #350270 |
Applications: | IHC |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Sheep IgG Polyclonal |
Applications: | WB, IHC |
Assay Range: | 0.469 - 30 ng/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #350207 |
Applications: | ELISA |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Kappa Monoclonal Clone #SAIC-43B-8 |
Applications: | WB, ELISA, ICC/IF, Flow |
Reactivity: | Human, Bovine (Negative), Canine (Negative), Porcine (Negative), Feline (Negative) |
Details: | Mouse IgG1 Monoclonal Clone #Hs-3 |
Applications: | IHC, WB, ELISA, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rat |
Details: | Goat IgG Polyclonal |
Applications: | WB, ELISA, ICC/IF |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
Reactivity: | Human |
Details: | Mouse IgG2b Monoclonal Clone #350207 |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #CLI-9 |
Applications: | IHC, WB, ICC/IF, IP |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #PSH04-33 |
Applications: | IHC, WB |