Cyclooxygenase Inhibitors Products
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
14 results for "Cyclooxygenase Inhibitors" in Products
14 results for "Cyclooxygenase Inhibitors" in Products
Cyclooxygenase Inhibitors Products
Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
Cyclooxygenase inhibitor; NSAID
| Chemical Name: | 2-[(2,6-Dichlorophenyl)amino]benzeneacetic acid sodium salt |
| Purity: | ≥99% (HPLC) |
Cyclooxygenase inhibitor (COX-1 > COX-2)
| Chemical Name: | 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; may be selective for COX-3
| Alternate Names: | Paracetamol |
| Chemical Name: | N-(4-Hydroxyphenyl)acetamide |
| Purity: | ≥99% (HPLC) |
Cyclooxygenase inhibitor
| Chemical Name: | 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase inhibitor; NSAID
| Chemical Name: | 2-Acetoxybenzoic acid |
| Purity: | ≥99% (HPLC) |
Selective cyclooxygenase-2 (COX-2) inhibitor
| Alternate Names: | SC 58635,Celebrex |
| Chemical Name: | 4-[5-(4-Methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Purity: | ≥99% (HPLC) |
Selective cyclooxygenase-2 (COX-2) inhibitor
| Alternate Names: | SC 58236 |
| Chemical Name: | 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide |
| Purity: | ≥99% (HPLC) |
Cyclooxygenase-2 (COX-2) inhibitor
| Chemical Name: | 5-Bromo-2-(4-fluorophenyl)-3-[4-(methylsulfonyl)phenyl]-thiophene |
| Purity: | ≥99% (HPLC) |
Cyclooxygenase-1 (COX-1) inhibitor
| Chemical Name: | 5-(4-Chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazole |
| Purity: | ≥98% (HPLC) |
Cyclooxygenase-2 (COX-2) inhibitor
| Chemical Name: | N-[2-Cyclohexyloxy-4-nitrophenyl]methanesulfonamide |
| Purity: | ≥99% (HPLC) |
NSAID, cyclooxygenase (COX-1) inhibitor. Also opener of KIR2.3
| Alternate Names: | CP 66248 |
| Chemical Name: | (Z)-5-Chloro-2,3-dihydro-3-(hydroxy-2-thienylmethylene)-2-oxo-1H-indole-1-carboxamide |
| Purity: | ≥99% (HPLC) |
Cyclooxygenase (COX-1) inhibitor
| Chemical Name: | 1-[[4,5-bis(4-Methoxyphenyl)-2-thiazolyl]carbonyl]-4-methylpiperazine hydrochloride |
| Purity: | ≥98% (HPLC) |
Selective and potent COX-2 inhibitor
| Chemical Name: | 4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonamide |
| Purity: | ≥99% (HPLC) |
Calcium-activated chloride channel blocker; NSAID. Also activates TRPC6
| Chemical Name: | 2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid |
| Purity: | ≥99% (HPLC) |
