DYRK2 Products
DYRK2 (Dual-specificity tyrosine [Y] phosphorylation regulated kinase 2) is a member of the MNB/DYRK subfamily, CMGC Ser/Thr protein kinase family of enzymes. DYRK2 is expressed in multiple tissues and shows dual substrate specificity. Autophosphorylation on Tyr382 leads to self-activation, while target proteins are Ser/Thr phosphorylated. Targets include NFATc, glycogen synthase, and p53. p53 phosphorylation on Ser46 by DYRK2 leads to cell apoptosis in response to DNA damage. Human DYRK2 is 601 amino acids (aa) in length, and contains one kinase catalytic domain (aa 222-535).
44 results for "DYRK2" in Products
44 results for "DYRK2" in Products
DYRK2 Products
DYRK2 (Dual-specificity tyrosine [Y] phosphorylation regulated kinase 2) is a member of the MNB/DYRK subfamily, CMGC Ser/Thr protein kinase family of enzymes. DYRK2 is expressed in multiple tissues and shows dual substrate specificity. Autophosphorylation on Tyr382 leads to self-activation, while target proteins are Ser/Thr phosphorylated. Targets include NFATc, glycogen synthase, and p53. p53 phosphorylation on Ser46 by DYRK2 leads to cell apoptosis in response to DNA damage. Human DYRK2 is 601 amino acids (aa) in length, and contains one kinase catalytic domain (aa 222-535).
| Reactivity: | Human, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #599542 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody - BSA Free [NBP1-76560]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-Immunocytochemistry-NBP1-76560-img0003.jpg "Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody - BSA Free [NBP1-76560]")
| Reactivity: | Human |
| Details: | Mouse IgG3 Kappa Monoclonal Clone #6E2 |
| Applications: | WB, ELISA, ICC/IF |
![Western Blot: DYRK2 Antibody (6E2) [H00008445-M02]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-6E2-Western-Blot-H00008445-M02-img0004.jpg "Western Blot: DYRK2 Antibody (6E2) [H00008445-M02]")
| Applications: | WB, ELISA, MA, AP, Enzyme Activity |
![SDS-PAGE: Recombinant Human DYRK2 GST (N-Term) Protein [H00008445-P01]](https://resources.bio-techne.com/images/products/DYRK2-Recombinant-Protein-SDS-Page-H00008445-P01-img0001.jpg "SDS-PAGE: Recombinant Human DYRK2 GST (N-Term) Protein [H00008445-P01]")
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #3G5 |
| Applications: | WB, ELISA |
![Western Blot: DYRK2 Antibody (3G5) [H00008445-M01]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-3G5-Western-Blot-H00008445-M01-img0004.jpg "Western Blot: DYRK2 Antibody (3G5) [H00008445-M01]")
| Applications: | WB, ELISA, MA, AP |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #4G11 |
| Applications: | WB, ELISA |
![Western Blot: DYRK2 Antibody (4G11) [H00008445-M03]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-4G11-Western-Blot-H00008445-M03-img0002.jpg "Western Blot: DYRK2 Antibody (4G11) [H00008445-M03]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody [NBP2-58747]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-58747-img0001.jpg "Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody [NBP2-58747]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Applications: | AC |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | ICC/IF |
![Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody [NBP1-89516]](https://resources.bio-techne.com/images/products/DYRK2-Antibody-Immunocytochemistry-Immunofluorescence-NBP1-89516-img0008.jpg "Immunocytochemistry/ Immunofluorescence: DYRK2 Antibody [NBP1-89516]")
Potent and selective DYRK inhibitor; orally bioavailable.
| Chemical Name: | (5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-4(5H)-thiazolone |
| Purity: | ≥95% (HPLC) |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, ICC/IF |