24 results for "EGF Receptor Inhibitors" in Products
EGF Receptor Inhibitors Products
Orally active, selective EGFR inhibitor
Chemical Name: | N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine |
Purity: | ≥98% |
Potent and selective dual ErbB2 (HER-2) and EGFR inhibitor
Chemical Name: | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-4-quinazolinamine |
Purity: | ≥98% (HPLC) |
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
Chemical Name: | 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Purity: | ≥98% (HPLC) |
Potent ErbB receptor family inhibitor
Chemical Name: | 5E-4-Amino-6-(4-benzyloxy-3-chlorophenylamino)pyrimidine-5-carboxaldehyde N-(2-morpholin-4-ylethyl) oxime hydrochloride |
Purity: | ≥97% |
Potent, reversible EGFR tyrosine kinase inhibitor
Chemical Name: | N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
Purity: | ≥98% (HPLC) |
Highly potent EGFR-kinase inhibitor
Alternate Names: | Tyrphostin AG 1478 |
Chemical Name: | N-(3-Chlorophenyl)-6,7-dimethoxy-4-quinazolinanine hydrochloride |
Purity: | ≥98% (HPLC) |
Potent ErbB receptor family inhibitor
Chemical Name: | N4-(3-Bromophenyl)-N6-methyl-pyrido[3,4-d]pyrimidine-4,6-diamine |
Purity: | ≥99% |
Potent HER2 receptor tyrosine kinase and EGFR kinase inhibitor
Chemical Name: | (2E)-N-[4-[[3-Chloro-4-(2-pyridinylmethoxy)phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide |
Purity: | ≥98% |
EGFR-kinase inhibitor. Also JAK2, JAK3 inhibitor
Chemical Name: | (E)-2-Cyano-3-(3,4-dihydrophenyl)-N-(phenylmethyl)-2-propenamide |
Purity: | ≥99% |
Highly potent EGFR and ErbB2 inhibitor; inhibts wild type and mutated receptors
Chemical Name: | (4-Fluorophenyl)methyl N-[2-[(1-methyl-1H-pyrazol-4-yl)amino]-4-pyrimidinyl]-N-[3-[(1-oxo-2-propen-1-yl)amino]phenyl]carbamate |
Purity: | ≥98% (HPLC) |
Potent EGFR kinase inhibitor
Alternate Names: | CI 1033,PD 183805 |
Chemical Name: | N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]-6-quinazolinyl]-2-propenamide dihydrochloride |
Purity: | ≥98% (HPLC) |
Potent and selective ErbB2 inhibitor
Chemical Name: | N6-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-N4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]-4,6-quinazolinediamine |
Purity: | ≥98% |
Potent EGFR and VEGFR inhibitor
Chemical Name: | 6-[4-[(4-Ethyl-1-piperazinyl)methyl]phenyl]-N-[(1R)-1-phenylethyl]-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Purity: | ≥98% |
Potent EGFR-kinase inhibitor
Chemical Name: | 4-[4-[[(1R)-1-Phenylethyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-6-yl]phenol hydrochloride |
Purity: | ≥98% (HPLC) |
Potent dual EGFR/ErbB2 inhibitor; orally active
Chemical Name: | N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[2-[[[2-(methylsulfonyl)ethyl]amino]methyl]-4-thiazolyl]-4-quinazolinamine dihydrochloride |
Purity: | ≥97% |
Inhibitor of EGFR mutants
Chemical Name: | 7-(Diethylamino)-3-(5-methyl-2-benzoxazolyl)-2H-1-benzopyran-2-one |
Purity: | ≥98% |
Potent irreversible pan ErbB inhibitor
Alternate Names: | PF00299804 |
Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]-4-(1-piperidinyl)-2-butenamide |
Purity: | ≥98% (HPLC) |
Potent dual specificity EGFR/HER2 inhibitor; active in vivo
Alternate Names: | BIBW2992 |
Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-2-butenamide dimaleate |
Purity: | ≥98% (HPLC) |
Potent and irreversible EGFR inhibitor; orally bioavailable
Chemical Name: | (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide |
Purity: | ≥97% |
Selective ErbB2 inhibitor
Alternate Names: | Tyrphostin AG 825 |
Chemical Name: | 3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-2-propenamide |
Potent and selective ErbB2 inhibitor
Chemical Name: | 1-[4-[4-[[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole |
Purity: | ≥99% |
Potent VEGFR-2 inhibitor, also inhibits EGFR and RET oncoproteins activity
Chemical Name: | N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-4-quinazolinamine |
Purity: | ≥98% |
Potent mutant-selective EGFR inhibitor
Chemical Name: | N-[3-[[5-Chloro-2-[[2-methoxy-4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]oxy]phenyl]-2-propenamide |
Purity: | ≥98% (HPLC) |
Negative control for PP 2 (Cat. No. 1407)
Chemical Name: | 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Purity: | ≥98% |