Endosialin/CD248 Products
Endosialin, also known as CD248 and tumor endothelial marker 1 (Tem1), is a 165 kDa transmembrane O-glycosylated protein that contains one C-type lectin, one Sushi, one EGF-like domain and a mucin-like stalk in its extracellular domain (ECD). It is expressed on activated perivascular and stromal cells in embyronic and tumor neovasculature but is downregulated in quiescent vasculature. Endosialin regulates pericyte proliferation, migration, and adhesion to matrix Fibronectin and Collagens I and IV. It is also required for lymph node and spleen remodeling during immune responses. Within the ECD, mouse Endosialin shares 76% and 93% aa sequence identity with human and rat Endosialin, respectively.
165 results for "Endosialin/CD248" in Products
165 results for "Endosialin/CD248" in Products
Endosialin/CD248 Products
Endosialin, also known as CD248 and tumor endothelial marker 1 (Tem1), is a 165 kDa transmembrane O-glycosylated protein that contains one C-type lectin, one Sushi, one EGF-like domain and a mucin-like stalk in its extracellular domain (ECD). It is expressed on activated perivascular and stromal cells in embyronic and tumor neovasculature but is downregulated in quiescent vasculature. Endosialin regulates pericyte proliferation, migration, and adhesion to matrix Fibronectin and Collagens I and IV. It is also required for lymph node and spleen remodeling during immune responses. Within the ECD, mouse Endosialin shares 76% and 93% aa sequence identity with human and rat Endosialin, respectively.
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #458606 |
| Applications: | ICC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Immunohistochemistry: Endosialin/CD248/TEM1 Antibody - BSA Free [NBP1-77310]](https://resources.bio-techne.com/images/products/Endosialin-CD248-TEM1-Antibody-Immunofluorescence-NBP1-77310-img0003.jpg "Immunohistochemistry: Endosialin/CD248/TEM1 Antibody - BSA Free [NBP1-77310]")
| Source: | NS0 |
| Accession #: | Q9HCU0 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Endosialin/CD248/TEM1 AntibodyBSA Free [NBP1-77311]](https://resources.bio-techne.com/images/products/Endosialin-CD248-TEM1-Antibody-Western-Blot-NBP1-77311-img0005.jpg "Western Blot: Endosialin/CD248/TEM1 AntibodyBSA Free [NBP1-77311]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: Endosialin/CD248/TEM1 Antibody [NBP2-14462]](https://resources.bio-techne.com/images/products/Endosialin-CD248-TEM1-Antibody-Immunocytochemistry-Immunofluorescence-NBP2-14462-img0012.jpg "Immunocytochemistry/ Immunofluorescence: Endosialin/CD248/TEM1 Antibody [NBP2-14462]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI4B8 |
| Applications: | WB |
![Western Blot: Endosialin/CD248/TEM1 Antibody (OTI4B8) [NBP2-46129]](https://resources.bio-techne.com/images/products/Endosialin-CD248-TEM1-Antibody-4B8-Western-Blot-NBP2-46129-img0001.jpg "Western Blot: Endosialin/CD248/TEM1 Antibody (OTI4B8) [NBP2-46129]")
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Endosialin/CD248/TEM1 Antibody [NBP2-99057]](https://resources.bio-techne.com/images/products/Endosialin-CD248-TEM1-Antibody-Immunohistochemistry-Paraffin-NBP2-99057-img0001.jpg "Immunohistochemistry-Paraffin: Endosialin/CD248/TEM1 Antibody [NBP2-99057]")
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2A7 |
| Applications: | WB, ELISA |
| Applications: | WB |
![Western Blot: Endosialin/CD248/TEM1 Overexpression Lysate [NBP2-06637]](https://resources.bio-techne.com/images/products/TEM1-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-06637-img0001.jpg "Western Blot: Endosialin/CD248/TEM1 Overexpression Lysate [NBP2-06637]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
| Applications: | AC |
| Applications: | AC |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Human IgG1 Monoclonal Clone #ontuxizumab |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Mouse IgG2B Monoclonal Clone #OTI4B8 |
| Applications: | WB |