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Erythropoietin R Products

Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

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153 results for "Erythropoietin R" in Products

Erythropoietin R Products

Erythropoietin (Epo) is a 30-kDa, heavily glycosylated protein produced primarily by the kidney. It is the principal factor that regulates erythropoiesis. The production of Epo by kidney cells is increased in response to hypoxia or anemia. The cDNAs for Epo have been cloned from many species. The mature proteins from the various species are highly conserved, exhibiting greater than 80% sequence identity at the amino acid level.

The biological effects of Epo are mediated by the Erythropoietin receptor (Epo R). At the protein sequence level, the human Epo R is approximately 83% identical to the mouse protein. As a result of alternative splicing of the Epo R gene, cDNA clones encoding truncated soluble forms of Epo R have been found. Recombinant soluble Epo R binds Epo with high affinity and is a potent Epo antagonist.

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Applications: IHC, WB, ICC/IF, Simple Western
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, IP
Reactivity: Human
Applications: Neut
Reactivity: Human
Applications: ELISA
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: AC
Catalog #: NBP2-89615
Applications: WB
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: AC
Applications: ICC/IF
Reactivity: Human
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA

Recombinant Monoclonal Antibody

Applications: WB, Flow, IP
Reactivity: Human
Applications: WB, Flow, IP
Reactivity: Human
Applications: WB, Flow, IP
Reactivity: Human
Applications: WB, Flow, IP
Reactivity: Human
Applications: WB, Flow, IP
Reactivity: Human
Applications: IHC, WB, ICC/IF, Simple Western
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF, Simple Western
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ICC/IF, Simple Western
Reactivity: Human, Mouse, Rat
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