Skip to main content

FGF acidic/FGF1 Products

FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.

FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.

Products:

Show More

70 results for "FGF acidic/FGF1" in Products

Back to Search Results
Apply

70 results for "FGF acidic/FGF1" in Products

FGF acidic/FGF1 Products

FGF acidic/FGF1, also known as ECGF and HBGF-1, is a secreted mitogen that stimulates the proliferation of all cells of mesodermal origin and many cells of neuroectodermal, ectodermal, and endodermal origin. It plays a number of roles in development, regeneration, and angiogenesis.

FGF1 is released extracellularly as a disulfide-linked homodimer and is stored in complex with extracellular heparan sulfate. The association of FGF1 with heparan sulfate is a prerequisite for its subsequent interaction with FGF receptors. Internalized FGF1 can translocate to the cytosol and to the nucleus. Intracellular FGF1 functions as a survival factor by inhibiting p53 activity and proapoptotic signaling.

Products:

Show More
Applications: WB, Simple Western, IHC, Neut
Reactivity: Human
Applications: IHC, WB, ELISA, ICC/IF, IP
Reactivity: Human, Plant
Applications: WB, Neut
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB, Neut
Reactivity: Bovine
Applications: BA
Applications: WB, IHC
Reactivity: Human
Applications: WB
Reactivity: Human
Applications: WB, ICC/IF
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: WB, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat, Porcine
Applications: IHC, ELISA
Reactivity: Zebrafish
Applications: IHC, WB, ICC/IF
Reactivity: Human, Porcine
Applications: WB
Applications: WB
Applications: WB
Applications: WB
Results Per Page
5 10 25 50
/ 3