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Frizzled-6 Products

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca2+ Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

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47 results for "Frizzled-6" in Products

47 results for "Frizzled-6" in Products

Frizzled-6 Products

This group of G protein-coupled receptors consists of 10 structurally-related, seven transmembrane proteins with a divergent N-terminal signal peptide and a variable-length C-terminal tail. The Frizzled family proteins contain a highly conserved cysteine-rich domain and a variable length linker region. Frizzled proteins function as receptors for Wnt proteins and can activate canonical Wnt/beta-catenin signaling as well as non-canonical pathways (Planar Cell Polarity and Wnt/Ca2+ Pathways). Wnt/Frizzled signaling is involved in a variety of developmental processes including cell fate determination, cell polarity, tissue patterning, and control of cell proliferation. Activation of a given Wnt/Frizzled signaling cascade is dependent on the Wnt ligand and the cell context. Frizzled proteins also form co-receptor complexes with LRP, ROR, and Ryk molecules.

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Applications: WB, Flow, IHC, CyTOF-ready
Reactivity: Mouse
Applications: WB, Flow, IHC, CyTOF-ready
Reactivity: Human
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB
Reactivity: Mouse
Applications: WB
Reactivity: Mouse
Applications: IHC, ICC/IF
Reactivity: Human, Monkey, Primate
Applications: IHC, WB
Reactivity: Human
Applications: WB, ELISA, MA, AP
Applications: WB
Reactivity: Human
Applications: WB
Applications: WB
Applications: ELISA
Applications: ELISA
Applications: AC
Applications: AC
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA, ICC/IF
Reactivity: Human, Mouse, Rat
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