G-CSFR/CD114: cDNA Clones
Human G-CSFR is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSFR exist that differ in their transmembrane C-terminal region. Human and mouse G-CSFR are 64% identical at the aa level. G-CSFR is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.
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2 results for "G-CSFR/CD114 cDNA Clones" in Products
2 results for "G-CSFR/CD114 cDNA Clones" in Products
G-CSFR/CD114: cDNA Clones
Human G-CSFR is 836 amino acids (aa) in length, with a 23 aa signal sequence, a 604 aa extracellular region, a 26 aa transmembrane segment, and a 183 aa cytoplasmic domain. As a result of alternative splicing, at least four isoforms of G-CSFR exist that differ in their transmembrane C-terminal region. Human and mouse G-CSFR are 64% identical at the aa level. G-CSFR is expressed in mature neutrophils, neutrophilic precursors, myeloid leukemia cells, and placenta.
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