Galanin R2/GALR2: cDNA Clones

Galanin R2 (GALR2) is one of three 54-60 kDa G-protein coupled multipass transmembrane receptors for the galanin neuropeptide. Galanin is co-expressed with and modulates noradrenaline and serotonin systems. GALR2 is thought to modulate growth and apoptosis. Unlike GALR and GALR3, it is thought to be anti-depressive. GALR2 mRNA is found mainly in the central nervous system (except for cerebral cortex), but also in intestine, heart, kidney, liver and many cancers.