Galectin-1 Products
Galectin-1, also known as L-14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds Laminin, Fibronectin, Galectin-3BP/MAC-2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1.
Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting pro-inflammatory cytokine production. Galectin-1 can also modulate cell-cell as well as cell-matrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity.
Products:
155 results for "Galectin-1" in Products
155 results for "Galectin-1" in Products
Galectin-1 Products
Galectin-1, also known as L-14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds Laminin, Fibronectin, Galectin-3BP/MAC-2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1.
Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting pro-inflammatory cytokine production. Galectin-1 can also modulate cell-cell as well as cell-matrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity.
Products:
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, CyTOF-ready, ICFlow |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, CyTOF-ready, ICFlow |
Source: | E. coli |
Accession #: | P09382.2 |
Applications: | BA |
Sensitivity: | 0.129 ng/mL |
Applications: | ELISA |
Assay Range: | 0.313 - 20 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma, Saliva, Human Milk) |
Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies
Source: | E. coli |
Accession #: | P16045 |
Applications: | BA |
Assay Range: | 125 - 8,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #933133 |
Applications: | WB, Simple Western, IHC |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB |
Reactivity: | Human |
Details: | Mouse IgG2b Lambda Monoclonal Clone #1E8-1B2 |
Applications: | WB, ELISA, ICC/IF, IP |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF, IP |
Assay Range: | 0.312 - 20 ng/mL |
Applications: | ELISA |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, IHC |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #201002 |
Applications: | WB, Simple Western, IHC |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Lambda Monoclonal Clone #GAL1/1831 |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #201066 |
Applications: | WB, Simple Western |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB, ICC/IF, IP, KO |
Reactivity: | Mouse |
Details: | Rat IgG2b Monoclonal Clone #201002 |
Applications: | WB, IHC |
Recombinant Monoclonal Antibody.
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JM13-37 |
Applications: | IHC, WB, ICC/IF, Flow, IP |
Alkylating agent; chemotherapeutic
Chemical Name: | 2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide |
Purity: | ≥99% (HPLC) |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #GAL1/2499R |
Applications: | IHC, WB, ELISA, MA |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies