GDF-3 Products
GDF-3 (Growth Differentiation Factor-3; Vgr-2) is a TGF-beta superfamily member that is expressed in undifferentiated embryonic stem (ES) cells, white adipose tissue, and the brain. GDF-3 is upregulated in adipocytes by a high-fat diet, promoting adipogenesis and obesity.
Both proGDF-3 and mature GDF-3 lacking the propeptide can oppose BMP activity. Inhibition of BMP-2 signaling by GDF-3 supports the pluripotency of ES cells. During embryogenesis, GDF-3 cooperates with GDF-1, plays a role in anterior visceral endoderm development. GDF-3 signals through the receptors Activin RIB/ALK-4 and ALK-7.
Products:
137 results for "GDF-3" in Products
137 results for "GDF-3" in Products
GDF-3 Products
GDF-3 (Growth Differentiation Factor-3; Vgr-2) is a TGF-beta superfamily member that is expressed in undifferentiated embryonic stem (ES) cells, white adipose tissue, and the brain. GDF-3 is upregulated in adipocytes by a high-fat diet, promoting adipogenesis and obesity.
Both proGDF-3 and mature GDF-3 lacking the propeptide can oppose BMP activity. Inhibition of BMP-2 signaling by GDF-3 supports the pluripotency of ES cells. During embryogenesis, GDF-3 cooperates with GDF-1, plays a role in anterior visceral endoderm development. GDF-3 signals through the receptors Activin RIB/ALK-4 and ALK-7.
Products:
| Reactivity: | Human, Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, IHC, ICC |
| Source: | CHO |
| Accession #: | Q9NR23 |
| Applications: | BA |
| Source: | CHO |
| Accession #: | Q07104 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #144728 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #741614 |
| Applications: | ICC |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #356613 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #878751 |
| Applications: | Neut |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #010 |
| Applications: | IHC, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: GDF-3 Antibody (010) [NBP2-89220]](https://resources.bio-techne.com/images/products/GDF-3-Antibody-010-Immunocytochemistry-Immunofluorescence-NBP2-89220-img0002.jpg "Immunocytochemistry/ Immunofluorescence: GDF-3 Antibody (010) [NBP2-89220]")
| Applications: | ELISA |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: GDF-3 Antibody [NBP1-86443]](https://resources.bio-techne.com/images/products/GDF-3-Antibody-Western-Blot-NBP1-86443-img0003.jpg "Western Blot: GDF-3 Antibody [NBP1-86443]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |
![Western Blot: GDF-3 Antibody [NBP2-98719]](https://resources.bio-techne.com/images/products/GDF-3-Antibody-Western-Blot-NBP2-98719-img0002.jpg "Western Blot: GDF-3 Antibody [NBP2-98719]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1219 |
| Applications: | WB |
| Applications: | WB |
![Western Blot: GDF-3 Overexpression Lysate [NBL1-11026]](https://resources.bio-techne.com/images/products/GDF3-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-11026-img0002.jpg "Western Blot: GDF-3 Overexpression Lysate [NBL1-11026]")
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GDF-3 Antibody [NBP2-99527]](https://resources.bio-techne.com/images/products/GDF-3-Antibody-Immunohistochemistry-Paraffin-NBP2-99527-img0002.jpg "Immunohistochemistry-Paraffin: GDF-3 Antibody [NBP2-99527]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GDF-3 Antibody [NBP2-98686]](https://resources.bio-techne.com/images/products/GDF-3-Antibody-Immunohistochemistry-Paraffin-NBP2-98686-img0002.jpg "Immunohistochemistry-Paraffin: GDF-3 Antibody [NBP2-98686]")
| Source: | E. coli |
| Accession #: | Q07104 |
| Applications: | Bind |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #010 |
| Applications: | IHC, ICC/IF |
| Reactivity: | Human, Rat, Porcine |
| Details: | Mouse IgG2b Kappa Monoclonal Clone #A7 |
| Applications: | WB |
| Applications: | AC |
| Reactivity: | Human |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C10 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ICC/IF |