gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
159 results for "gp130" in Products
159 results for "gp130" in Products
gp130 Products
Gp130, the common signal transducing receptor component shared by the functional receptor complexes of the IL-6 family of cytokines, belongs to the classI cytokine receptor family. Binding of IL-6 or IL-11 to either the membrane-anchored or soluble IL-6 R or IL-11 R, respectively, initiates the association of IL-6 R (IL-11 R) with gp130. The complex then undergoes homodimerization and signal transduction. For other IL-6 family cytokines, such as LIF and OSM, signal transduction is similarly triggered by the heterodimerization of gp130 with LIFR or OSM R.
| Sensitivity: |
0.05 ng/mL (Cell Culture Supernates) 0.08 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Applications: | ELISA |
| Assay Range: |
0.125 - 8 ng/mL (Cell Culture Supernates) 0.25 - 16 ng/mL (Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28105 |
| Applications: | IHC, Neut |
| Source: | Sf 21 (baculovirus) |
| Accession #: | P40189 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow, CyTOF-ready, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #29104 |
| Applications: | ELISA |
Simple Plex Human GP130 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
| Applications: | Simple Plex |
Create your custom Simple Plex cartridge for up to 8 targets. Choose from more than 250 targets across multiple species.
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | P40189 |
| Applications: | BA |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow, CyTOF-ready, ICC |
Control for use with Human gp130 Simple Plex Cartridge Kit
| Applications: | Ctrl, Simple Plex |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow |
| Source: | NS0 |
| Accession #: | Q6PDI9 |
| Applications: | BA |
gp130 agonist; brain penetrant and neuroprotectant
| Chemical Name: | N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine |
| Purity: | ≥98% (HPLC) |
Luminex High Performance Assays go through rigorous development, validation, and quality control testing to ensure you are getting the best performance out of your multiplex assay. Panels are customizable so you can order a selection of the analytes or the entire panel.
| Reactivity: | Mouse |
| Details: | Rat IgG1 Monoclonal Clone #125605 |
| Applications: | Neut |
Biotinylated
| Source: | HEK293 |
| Accession #: | AAA59155.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Rat |
| Details: | Mouse IgG1 Monoclonal Clone #745314 |
| Applications: | WB, Flow, CyTOF-ready |
| Reactivity: | Human, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: gp130/CD130 Antibody [NBP2-15776]](https://resources.bio-techne.com/images/products/gp130-CD130-Antibody-Western-Blot-NBP2-15776-img0009.jpg "Western Blot: gp130/CD130 Antibody [NBP2-15776]")
Biotinylated
| Source: | CHO |
| Accession #: | AAA59155.1 |
| Applications: | BA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #28126 |
| Applications: | Flow |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #125623 |
| Applications: | Flow, ICC |