GSK-3 beta Products
GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.
29 results for "GSK-3 beta" in Products
29 results for "GSK-3 beta" in Products
GSK-3 beta Products
GSK-3 is a Ser/Thr kinase first identified as an inactivator of Glycogen Synthase. GSK-3 acts as a multifunctional downstream switch that determines the output of numerous signaling pathways. There are two mammalian GSK-3 isoforms encoded by distinct genes, GSK-3 alpha and GSK-3 beta, which are structurally similar, but functionally non-identical. GSK-3a is inhibited by phosphorylation at S21 by Akt and other kinases. GSK-3 alpha and GSK-3 beta share 85% amino acid identity. Dysregulated GSK-3 has been implicated in several diseases including type II diabetes, Alzheimer's disease, bipolar disorder, and cancer.
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, CyTOF-ready, ICC, ICFlow |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #609739 |
Applications: | WB, ICC/IF, Flow, CyTOF-ready |