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HIF-2 alpha/EPAS1 Products

The hypoxia-inducible transcription factor 2 alpha is stabilized in hypoxic tissue and, similarly to HIF-1 alpha, complexes with aryl hydrocarbon receptor nuclear translocator (ARNT). Both the HIF-1 and HIF-2 complexes bind hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. HIF-1 and HIF-2 do not appear to be completely redundant, although specific functions are only beginning to be elucidated. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, indicating the potentially broad impact of gene regulation by both HIF-1 alpha and HIF-2 alpha.

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136 results for "HIF-2 alpha/EPAS1" in Products

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136 results for "HIF-2 alpha/EPAS1" in Products

HIF-2 alpha/EPAS1 Products

The hypoxia-inducible transcription factor 2 alpha is stabilized in hypoxic tissue and, similarly to HIF-1 alpha, complexes with aryl hydrocarbon receptor nuclear translocator (ARNT). Both the HIF-1 and HIF-2 complexes bind hypoxia-response elements (HREs) in the promoters of many genes involved in adapting to an environment of insufficient oxygen or hypoxia. HIF-1 and HIF-2 do not appear to be completely redundant, although specific functions are only beginning to be elucidated. Hypoxic tissue environments occur in vascular and pulmonary diseases as well as cancer, indicating the potentially broad impact of gene regulation by both HIF-1 alpha and HIF-2 alpha.

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Applications: IHC, WB, ELISA, ICC/IF, Flow, B/N, ChIP, Dual ISH-IHC, Func, GS, IP, KD, KO, PAGE, Simple Western
Reactivity: Human, Mouse, Rat, Primate, Rabbit, +6 More
Applications: IHC, WB, ELISA, ICC/IF, Flow, ChIP, Func, GS, IP, KD, Simple Western
Reactivity: Human, Mouse, Rat, Bovine, Hamster
Applications: WB, IHC
Reactivity: Human, Mouse, Rat
Applications: IHC, WB, ELISA, ICC/IF, Flow, ChIP, IP, KD, Simple Western
Reactivity: Human, Mouse, Rat, Rabbit, Hamster
Applications: WB, ChIP
Reactivity: Human, Rat
Applications: IHC, WB
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: WB, ICC
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: WB
Reactivity: Human
Applications: IHC
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: WB, ELISA, MA, AP
Applications: IHC
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody

Applications: WB, ELISA, MA, AP, PAGE
Applications: AC
Applications: AC
Applications: AC
Applications: ICC/IF
Reactivity: Human
Applications: ELISA, ICC/IF
Reactivity: Human

Recombinant monoclonal antibody expressed in HEK293F cells

Applications: ICC/IF
Reactivity: Human
Applications: IHC
Reactivity: Human, Mouse

Recombinant Monoclonal Antibody

Applications: IHC, WB
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: IHC, WB, ELISA, ICC/IF, Flow, ChIP, Dual ISH-IHC, Func, GS, IP, KD, KO, PAGE, Simple Western
Reactivity: Human, Mouse, Rat, Primate, Rabbit, +4 More
Applications: IHC, WB, ELISA, ICC/IF, Flow, ChIP, Func, GS, IP, KD, Simple Western
Reactivity: Human, Mouse, Rat, Bovine, Hamster

Contains 4 membranes - each spotted in duplicate with 26 different cell stress antibodies

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