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HLA-DR Products

HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily on B cells on which it presents antigenic peptides for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.

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3 results for "HLA-DR" in Products

3 results for "HLA-DR" in Products

HLA-DR Products

HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member and consists of a 34 kDa (alpha) subunit and one of several 28 kDa (beta) subunits. HLA-DR is expressed primarily on B cells on which it presents antigenic peptides for recognition by the T cell receptor on CD4+ T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.

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Applications: IHC, WB, ICC/IF, ELISA, Flow, B/N, CyTOF-ready, Dual ISH-IHC, Func, IP, MS
Reactivity: Human, Canine, Primate, Baboon
Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: IHC, Flow, IP
Reactivity: Sheep
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