IkB-alpha Products
The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.
108 results for "IkB-alpha" in Products
108 results for "IkB-alpha" in Products
IkB-alpha Products
The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.
Reactivity: | Human, Mouse, Rat |
Details: | Mouse IgG1 kappa Monoclonal Clone #6A920 |
Applications: | IHC, WB, ICC/IF, Flow, IP, +3 More |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
Reactivity: | Human, Mouse, Rat, Canine, Bovine, +1 More |
Details: | Mouse IgG1 kappa Monoclonal Clone #39A1413 |
Applications: | WB, ICC/IF, IP, Simple Western |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #417208 |
Applications: | WB, Simple Western, IHC, KO |
Reactivity: | Human, Mouse |
Details: | Sheep IgG Polyclonal |
Applications: | WB, ICC, KO |
Assay Range: | 31.2 - 2,000 pg/mL |
Applications: | ELISA |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB |
Irreversible inhibitor of TNF-α-induced IκBα phosphorylation
Alternate Names: | Bay 11-7083 |
Chemical Name: | (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile |
Purity: | ≥98% (HPLC) |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #4D4C4 |
Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ICC/IF |
Reactivity: | Human |
Details: | Mouse IgG1 Monoclonal Clone #4D4F2 |
Applications: | WB, ELISA, ICC/IF, Flow, CyTOF-ready |
E2 ubiquitin (Ub) conjugating enzymes inhibitor
Alternate Names: | Bay 11-7082 |
Chemical Name: | (2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile |
Purity: | ≥99% (HPLC) |
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
Alternate Names: | (-)-Arctigenin |
Chemical Name: | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
Purity: | ≥98% (HPLC) |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #SR1656 |
Applications: | WB, IP |
Applications: | AC |
Applications: | PAGE |
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Polyclonal |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #116 |
Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #JE56-65 |
Applications: | WB |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse |
Details: | Rabbit IgG Monoclonal Clone #SR1657 |
Applications: | WB, Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #116 |
Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #116 |
Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Rabbit IgG Monoclonal Clone #116 |
Applications: | WB, ELISA, IP |