IkB-alpha Products
The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.
110 results for "IkB-alpha" in Products
110 results for "IkB-alpha" in Products
IkB-alpha Products
The inhibitory IkB proteins (alpha, beta, epsilon) complex with and sequester NFkB family members in the cytoplasm, rendering these transcription factors inactive. When phosphorylated by an active IkB kinase (IKK) complex, IkB proteins are degraded by proteasomes, resulting in the release and nuclear translocation of active NFkB.
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #6A920 |
| Applications: | IHC, WB, ICC/IF, Flow, IP, +3 More |
![Knockout Validated: IkB-alpha Antibody (6A920) - BSA Free [NB100-56507]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-6A920-Knockout-Validated-NB100-56507-img0032.jpg "Western Blot: IkB-alpha Antibody (6A920) - BSA Free [NB100-56507]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #417208 |
| Applications: | WB, Simple Western, IHC, KO |
| Reactivity: | Human, Mouse, Rat, Canine, Bovine, +1 More |
| Details: | Mouse IgG1 kappa Monoclonal Clone #39A1413 |
| Applications: | WB, ICC/IF, IP, Simple Western |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
![Western Blot: IkB-alpha Antibody [NBP1-87761]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-Western-Blot-NBP1-87761-img0011.jpg "Western Blot: IkB-alpha Antibody [NBP1-87761]")
| Reactivity: | Human, Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB, ICC, KO |
| Assay Range: | 31.2 - 2,000 pg/mL |
| Applications: | ELISA |
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #4D4C4 |
| Applications: | IHC, WB, ELISA, ICC/IF, Flow, +1 More |
![Western Blot: IkB-alpha Antibody (4D4C4)BSA Free [NBP2-52517]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-4D4C4-Western-Blot-NBP2-52517-img0006.jpg "Western Blot: IkB-alpha Antibody (4D4C4)BSA Free [NBP2-52517]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB |
![Western Blot: IkB-alpha Antibody [NB120-22071]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-Western-Blot-NB120-22071-img0007.jpg "Western Blot: IkB-alpha Antibody [NB120-22071]")
Irreversible inhibitor of TNF-α-induced IκBα phosphorylation
| Alternate Names: | Bay 11-7083 |
| Chemical Name: | (2E)-3-[[4-(1,1-Dimethylethyl)phenyl]sulfonyl]-2-propenenitrile |
| Purity: | ≥98% (HPLC) |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #4D4F2 |
| Applications: | WB, ELISA, ICC/IF, Flow, CyTOF-ready |
![Western Blot: IkB-alpha Antibody (4D4F2)BSA Free [NBP2-52518]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-4D4F2-Western-Blot-NBP2-52518-img0004.jpg "Western Blot: IkB-alpha Antibody (4D4F2)BSA Free [NBP2-52518]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #8G1X10 |
| Applications: | IHC, WB |
E2 ubiquitin (Ub) conjugating enzymes inhibitor
| Alternate Names: | Bay 11-7082 |
| Chemical Name: | (2E)-3-[(4-Methylphenyl)sulfonyl]-2-propenenitrile |
| Purity: | ≥99% (HPLC) |
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
| Alternate Names: | (-)-Arctigenin |
| Chemical Name: | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
| Purity: | ≥98% (HPLC) |
| Applications: | AC |
Contains 4 membranes-each spotted in duplicate with 49 different antibodies to ubiquitin target proteins
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE56-65 |
| Applications: | WB |
![IkB-alpha [p Ser36] Antibody (JE56-65)](https://resources.bio-techne.com/images/products/nbp3-32773_rabbit-ikb-alpha-p-ser36-mab-je56-65-288202412442912.jpg "Western Blot: IkB-alpha [p Ser36] Antibody (JE56-65) [NBP3-32773]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #116 |
| Applications: | WB, ELISA, IP |
![Western Blot: IkB-alpha Antibody (116) [NBP2-90043]](https://resources.bio-techne.com/images/products/IkB-alpha-Antibody-116-Western-Blot-NBP2-90043-img0001.jpg "Western Blot: IkB-alpha Antibody (116) [NBP2-90043]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #SR1656 |
| Applications: | WB, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #SR1657 |
| Applications: | WB, Flow |
| Applications: | WB |
![Western Blot: IkB-alpha Overexpression Lysate [NBP2-06636]](https://resources.bio-techne.com/images/products/IKB-alpha-Overexpression-Lysate-Adult-Normal-Western-Blot-NBP2-06636-img0001.jpg "Western Blot: IkB-alpha Overexpression Lysate [NBP2-06636]")
| Applications: | PAGE |
| Applications: | AC |
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Rabbit IgG Monoclonal Clone #116 |
| Applications: | WB, ELISA, IP |
