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IL-11 Products

Interleukin-11, also known as AGIF, is a pleiotropic cytokine in the IL-6 family, which also includes LIF, CNTF, Oncostatin M, Cardiotrophin-1, IL-27, and IL-31. It is secreted by osteoblasts, synoviocytes, fibroblasts, chondrocytes, intestinal myofibroblasts, and trophoblasts. It is found in the plasma mainly during inflammation, and is considered to be primarily anti-inflammatory. It stimulates hematopoiesis and thrombopoiesis, regulates macrophage differentiation, and confers mucosal protection in the intestine. It has also been found to enhance T cell polarization toward Th2, promote B cell IgG production, increase osteoclast bone absorption, protect endothelial cells from oxidative stress, and regulate epithelial proliferation and apoptosis. IL-11 signals through a receptor complex that contains IL-11 R alpha and gp130. A soluble form of IL-11 R alpha can bind IL-11 and either form a signaling complex with gp130 on the cell surface or inhibit cell surface IL-11 R alpha/gp130 signaling.

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133 results for "IL-11" in Products

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133 results for "IL-11" in Products

IL-11 Products

Interleukin-11, also known as AGIF, is a pleiotropic cytokine in the IL-6 family, which also includes LIF, CNTF, Oncostatin M, Cardiotrophin-1, IL-27, and IL-31. It is secreted by osteoblasts, synoviocytes, fibroblasts, chondrocytes, intestinal myofibroblasts, and trophoblasts. It is found in the plasma mainly during inflammation, and is considered to be primarily anti-inflammatory. It stimulates hematopoiesis and thrombopoiesis, regulates macrophage differentiation, and confers mucosal protection in the intestine. It has also been found to enhance T cell polarization toward Th2, promote B cell IgG production, increase osteoclast bone absorption, protect endothelial cells from oxidative stress, and regulate epithelial proliferation and apoptosis. IL-11 signals through a receptor complex that contains IL-11 R alpha and gp130. A soluble form of IL-11 R alpha can bind IL-11 and either form a signaling complex with gp130 on the cell surface or inhibit cell surface IL-11 R alpha/gp130 signaling.

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Applications: BA

Analyzed by SEC-MALS

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Applications: WB, Neut
Reactivity: Human
Applications: Simple Plex

Simple Plex Human IL-11 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: WB, Neut
Reactivity: Mouse
Applications: WB
Reactivity: Human
Applications: WB, Neut
Reactivity: Human
Applications: WB, Neut
Reactivity: Human

Contains 4 membranes - each spotted in duplicate with 38 different obesity-related antibodies

Applications: WB
Reactivity: Mouse

Contains 4 membranes - each spotted in duplicate with 53 different angiogenesis antibodies

Applications: WB
Reactivity: Human
Reactivity: Mouse
Applications: WB, Neut
Reactivity: Mouse
Applications: Ctrl, Simple Plex

Control for use with Human IL-11 Simple Plex Cartridge Kit

Applications: BA

Contains 4 membranes-each spotted in duplicate with 58 different obesity-related antibodies

Applications: ELISA
Applications: WB, Neut
Reactivity: Human

Recombinant Monoclonal Antibody.

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