IL-12 Products
IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.
4 results for "IL-12" in Products
4 results for "IL-12" in Products
IL-12 Products
IL-12 (Interleukin-12) is a heterodimeric cytokine that consists of a p35 and a p40 subunit. p40 is also a subunit of the cytokine IL-23. IL-12 enhances the cytotoxic activity and induces IFN-gamma production in NK cells, T cells, and dendritic epidermal T cells, and it promotes a Th1 biased immune response. It signals through a receptor complex composed of IL-12 R beta 1 and IL-12 R beta 2. Both homodimeric p40, and IL-23 can bind to the IL-12 receptor, serving as non-signaling antagonists.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #24910 |
| Applications: | WB, IHC, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, ICC, Neut |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 Monoclonal Clone #27537 |
| Applications: | ICFlow |
Analyzed by SEC-MALS
| Source: | Sf 21 (baculovirus) |
| Accession #: | P29460 (p40) & P29459 (p35) |
| Applications: | BA |
