IL-1ra/IL-1F3 Products
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
7 results for "IL-1ra/IL-1F3" in Products
7 results for "IL-1ra/IL-1F3" in Products
IL-1ra/IL-1F3 Products
IL-1ra (IL-1 receptor antagonist) is a widely expressed acute phase protein that serves to dampen inflammation. IL-1ra binds to both IL-1 RI and IL-1 RII. It competitively inhibits IL-1 (alpha or beta) binding to IL-1 RI and does not trigger recruitment of the accessory molecule IL-1 R AcP or activation of IL-1 RI signaling. IL-1ra blocks the proinflammatory actions of IL-1 including Prostaglandin E2 and IL-6 release from endothelial cells, fever generation, thrombocytosis, the production of hepatic acute phase proteins, and neutrophil expansion and infiltration.
Source: | E. coli |
Accession #: | P18510 |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, Neut |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #10309 |
Applications: | Neut |
Source: | E. coli |
Accession #: | P25086.1 |
Applications: | BA |
Reactivity: | Human |
Details: | Goat IgG Polyclonal |
Applications: | WB, Neut |
Source: | E. coli |
Accession #: | Q29056 |
Applications: | BA |