IL-27 Products
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
95 results for "IL-27" in Products
95 results for "IL-27" in Products
IL-27 Products
IL-27 is a heterodimeric cytokine that is composed of EBI3 (which is related to the p40 subunit of IL-12 and IL-23) and p28 (which is related to the p35 chain of IL-12). IL-27 is expressed by monocytes, endothelial cells, and dendritic cells. It signals through a receptor complex composed of IL-27 R alpha/WSX-1/TCCR and gp130. IL-27 induces IL-12 receptor expression on naïve CD4+ T cells, sensitizing them to subsequent IL-12-induced Th1 development. It also functions as an anti-inflammatory cytokine by limiting T and NKT cell activity.
Products:
His-tag
| Source: | NS0 |
| Accession #: | Q14213.2 (EBI3) & AAM34498 (p28) |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | O35228 (EBI3) & Q8K3I6 (p28) |
| Applications: | BA |
| Assay Range: | 156 - 10,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB, Neut |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
