Jagged 1 Products
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of the heart, eye, and vertebrae, as well as a characteristic facial appearance.
Products:
92 results for "Jagged 1" in Products
92 results for "Jagged 1" in Products
Jagged 1 Products
Jagged 1 is a transmembrane glycoprotein in the Delta-Serrate-Lag-2 (DSL) family of ligands that activate Notch proteins. Jagged 1 is widely expressed in adult and fetal tissues. Jagged-Notch signaling specifies cell fate, regulates pattern formation, defines boundaries between different cell types, and modulates cell proliferation and differentiation. It plays a key role in vascular, hematopoietic, myogenic, and neurogenic development. Mutations in human Jagged 1 are the cause of Alagille syndrome, an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of the heart, eye, and vertebrae, as well as a characteristic facial appearance.
Products:
| Source: | CHO |
| Accession #: | P78504 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2b Monoclonal Clone #241002 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2B Monoclonal Clone #188331 |
| Applications: | Flow, CyTOF-ready |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI3A10 |
| Applications: | IHC, WB |
| Source: | NS0 |
| Accession #: | Q63722.2 |
| Applications: | BA |
| Assay Range: | 0.312 - 20 ng/mL |
| Applications: | ELISA |
| Source: | HEK293 |
| Accession #: | P78504.3 |
| Applications: | BA |
| Source: | NS0 |
| Accession #: | Q9QXX0.1 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG1 kappa Monoclonal Clone #1E12 |
| Applications: | IHC, WB, ELISA, KO |
![Western Blot: Jagged 1 Antibody (1E12) [H00000182-M01A]](https://resources.bio-techne.com/images/products/Jagged-1-Antibody-1E12-Western-Blot-H00000182-M01A-img0001.jpg "Western Blot: Jagged 1 Antibody (1E12) [H00000182-M01A]")
Biotinylated
| Source: | CHO |
| Accession #: | P78504.3 |
| Applications: | BA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ELISA, ICC/IF |
![Western Blot: Jagged 1 Antibody [NB600-1161]](https://resources.bio-techne.com/images/products/Jagged-1-Antibody-Western-Blot-NB600-1161-img0004.jpg "Western Blot: Jagged 1 Antibody [NB600-1161]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2A Monoclonal Clone #OTI3A10 |
| Applications: | IHC, WB |
![Western Blot: Jagged 1 Antibody (OTI3A10) [NBP2-45467]](https://resources.bio-techne.com/images/products/Jagged-1-Antibody-OTI3A10-Western-Blot-NBP2-45467-img0009.jpg "Western Blot: Jagged 1 Antibody (OTI3A10) [NBP2-45467]")
| Source: | CHO |
| Accession #: | P78504 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Assay Range: | 125 - 8,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | Q63722 |
| Applications: | BA |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2b Monoclonal Clone #188331 |
| Applications: | Flow |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208]](https://resources.bio-techne.com/images/products/Jagged-1-Antibody-Immunohistochemistry-Paraffin-NBP1-90208-img0012.jpg "Immunohistochemistry-Paraffin: Jagged 1 Antibody [NBP1-90208]")