Kremen-2: Proteins and Enzymes
Kremen (Kringle-containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Two related members, Kremen-1 and -2, have been identified. Kremens bind a subset of the secreted Dickkopf (Dkk) proteins with high affinity. The canonical Wnt signaling pathway receptor complex composed of Wnt, the seven-transmembrane domain receptor Frizzled, and the receptor-related protein 5/6 (LRP5/6) coreceptor, is modulated by Kremens and Dkk proteins.
3 results for "Kremen-2 Proteins and Enzymes" in Products
3 results for "Kremen-2 Proteins and Enzymes" in Products
Kremen-2: Proteins and Enzymes
Kremen (Kringle-containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Two related members, Kremen-1 and -2, have been identified. Kremens bind a subset of the secreted Dickkopf (Dkk) proteins with high affinity. The canonical Wnt signaling pathway receptor complex composed of Wnt, the seven-transmembrane domain receptor Frizzled, and the receptor-related protein 5/6 (LRP5/6) coreceptor, is modulated by Kremens and Dkk proteins.
| Source: | NS0 |
| Accession #: | Q8NCW0 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | Q8K1S7 |
| Applications: | Bind |
| Source: | NS0 |
| Accession #: | XP_220206 |
| Applications: | Bind |