Kynureninase: Proteins and Enzymes
Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3-hydroxyanthranilic acid and alanine. KYNU degrades dietary tryptophan in the liver and is involved in the de novo biosynthesis of NAD+. In immune system cells, such as macrophages and microglia, KYNU catalyzes inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer's, stroke, epilepsy, and Huntington's disease.
2 results for "Kynureninase Proteins and Enzymes" in Products
2 results for "Kynureninase Proteins and Enzymes" in Products
Kynureninase: Proteins and Enzymes
Kynureninase (KYNU) catalyzes the hydrolytic cleavage of the amino acids L-kynurenine and L-3-hydroxykynurenine to give either anthranilic acid or 3-hydroxyanthranilic acid and alanine. KYNU degrades dietary tryptophan in the liver and is involved in the de novo biosynthesis of NAD+. In immune system cells, such as macrophages and microglia, KYNU catalyzes inflammatory quinolinic acid (QA) production, which may cause neuronal damage in AIDS-related dementia complex, Alzheimer's, stroke, epilepsy, and Huntington's disease.
| Source: | Sf 21 (baculovirus) |
| Accession #: | NP_003928 |
| Applications: | EnzAct |
| Applications: | AC |