Lipocalin-2/NGAL Products
Lipocalin-2/NGAL (Neutrophil Gelatinase-associated Lipocalin) is a secreted carrier protein that acts in the innate immune response, differentiation, tumorigenesis, and cell survival. It is induced in macrophages, glial cells, and epithelial cells during inflammation, anemia, and hypoxia. Lipocalin-2 binds catecholate siderophores which are secreted by bacteria and are required for bacterial iron uptake. Lipocalin-2 functions as a bacteriostatic agent in the innate immune response by limiting the bacterial iron supply. Iron uptake by Lipocalin-2 into mammalian cells is important for the regulation of iron-sensitive gene transcription. In the kidney, Lipocalin-2-mediated iron trafficking is required for protection from renal injury.
10 results for "Lipocalin-2/NGAL" in Products
10 results for "Lipocalin-2/NGAL" in Products
Lipocalin-2/NGAL Products
Lipocalin-2/NGAL (Neutrophil Gelatinase-associated Lipocalin) is a secreted carrier protein that acts in the innate immune response, differentiation, tumorigenesis, and cell survival. It is induced in macrophages, glial cells, and epithelial cells during inflammation, anemia, and hypoxia. Lipocalin-2 binds catecholate siderophores which are secreted by bacteria and are required for bacterial iron uptake. Lipocalin-2 functions as a bacteriostatic agent in the innate immune response by limiting the bacterial iron supply. Iron uptake by Lipocalin-2 into mammalian cells is important for the regulation of iron-sensitive gene transcription. In the kidney, Lipocalin-2-mediated iron trafficking is required for protection from renal injury.
Sensitivity: | 8.8 pg/mL |
Applications: | ELISA |
Assay Range: | 78.1 - 5,000 pg/mL (Cell Culture Supernates, Serum, Platelet-poor EDTA Plasma, Platelet-poor Heparin Plasma, Urine) |
Sensitivity: | 0.04 ng/mL |
Applications: | ELISA |
Assay Range: | 0.156 - 10 ng/mL (Cell Culture Supernates, Serum, Heparin Plasma, Saliva, Urine) |
Reactivity: | Mouse |
Details: | Goat IgG Polyclonal |
Applications: | WB, Simple Western, IHC, IP |
Assay Range: | 7.81 - 500 pg/mL |
Applications: | ELISA |
Assay Range: | 78.1 - 5,000 pg/mL |
Applications: | ELISA |
Source: | NS0 |
Accession #: | P11672 |
Applications: | Bind |
Source: | NS0 |
Accession #: | P80188 |
Applications: | Bind |
Reactivity: | Human |
Details: | Rat IgG2a Monoclonal Clone #220310 |
Applications: | WB, IHC |
Reactivity: | Human |
Details: | Rat IgG2b Monoclonal Clone #220322 |
Applications: | ELISA |
Reactivity: | Human |
Details: | Mouse IgG1 kappa Monoclonal Clone #04 |
Applications: | WB, ELISA |