MAP3K8/Tpl2/COT: Lysates
MAP3K8, also called Tpl2 (tumor progression locus 2) or COT (Cancer Osaka Thyroid oncogene), is a cytosolic Ser/Thr kinase. MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. MAP3K8 activates I kappa B kinases and induces the nuclear production of NF-kappa B.
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MAP3K8/Tpl2/COT: Lysates
MAP3K8, also called Tpl2 (tumor progression locus 2) or COT (Cancer Osaka Thyroid oncogene), is a cytosolic Ser/Thr kinase. MAP3K8 is one of the MAP kinase kinase (MAPKK) kinases that regulates the ERK1/ERK2 pathway in response to IL-1, facilitating IL-8 and MIP-1 beta production. MAP3K8 activates I kappa B kinases and induces the nuclear production of NF-kappa B.
| Applications: | WB |
![Western Blot: MAP3K8/Tpl2/COT Overexpression Lysate [NBL1-12859]](https://resources.bio-techne.com/images/products/MAP3K8-Overexpression-Lysate-Adult-Normal-Western-Blot-NBL1-12859-img0002.jpg "Western Blot: MAP3K8/Tpl2/COT Overexpression Lysate [NBL1-12859]")