MDM2/HDM2 Products
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
82 results for "MDM2/HDM2" in Products
82 results for "MDM2/HDM2" in Products
MDM2/HDM2 Products
MDM2 is a key regulator of p53 tumor suppressor protein activity and stability. MDM2 binds to and inhibits the transactivation domain of p53. In addition, MDM2 controls p53 stability by functioning as its E3 ligase in ubiquitination and by shuttling p53 from the nucleus to the cytoplasm for subsequent degradation. The importance of the p53/MDM2 relationship is underscored by the existence of an autoregulatory feedback loop whereby activated p53 transcriptionally upregulates the expression of its own inhibitor, MDM2.
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, WB, ICC/IF, IP, ChIP |
![Western Blot: MDM2/HDM2 Antibody [NBP2-17247]](https://resources.bio-techne.com/images/products/MDM2-HDM2-Antibody-Western-Blot-NBP2-17247-img0027.jpg "Western Blot: MDM2/HDM2 Antibody [NBP2-17247]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JE64-20 |
| Applications: | WB |
![MDM2/HDM2 [p Ser166] Antibody (JE64-20)](https://resources.bio-techne.com/images/products/nbp3-32777_rabbit-mdm2-hdm2-p-ser166-mab-je64-20-288202412461655.jpg "Western Blot: MDM2/HDM2 [p Ser166] Antibody (JE64-20) [NBP3-32777]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #SMP14 |
| Applications: | IHC, WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB, ELISA, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #SMP14 |
| Applications: | IHC, WB, IP |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #SMP14 |
| Applications: | IHC, WB, IP |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |
| Reactivity: | Human, Mouse |
| Details: | Mouse IgG2A Monoclonal Clone #HDM2-323 |
| Applications: | WB, ELISA |