MEK1/MEK2 Products
MEK1 and MEK2, also known as MAP2K1 and MAP2K2, are activated in response to mitogenic stimuli. Activation occurs through dual phosphorylation at S218/S222 of MEK1 and S222/S226 of MEK2 by several upstream MAP3Ks. Both MEK1 and MEK2 are dual-specificity protein kinases, phosphorylating and activating ERK1 and ERK2 at Thr and Tyr positions.
Products:
13 results for "MEK1/MEK2" in Products
13 results for "MEK1/MEK2" in Products
MEK1/MEK2 Products
MEK1 and MEK2, also known as MAP2K1 and MAP2K2, are activated in response to mitogenic stimuli. Activation occurs through dual phosphorylation at S218/S222 of MEK1 and S222/S226 of MEK2 by several upstream MAP3Ks. Both MEK1 and MEK2 are dual-specificity protein kinases, phosphorylating and activating ERK1 and ERK2 at Thr and Tyr positions.
Products:
Recombinant Monoclonal Antibody.
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #1020E |
| Applications: | WB |
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit Polyclonal |
| Applications: | IHC, WB |
![MEK1/2 [p Ser221, p Ser217] Antibody - BSA Free](https://resources.bio-techne.com/images/products/nbp3-20686_rabbit-mek1-2-p-ser217-p-ser221-pab-2711202419553094.jpg "Immunohistochemistry: MEK1/2 [p Ser221, p Ser217] Antibody - BSA Free [NBP3-20686] -")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #SR1751 |
| Applications: | IHC, WB, ICC/IF, IP |
| Reactivity: | Mouse, Rat |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: MEK1/2 AntibodyBSA Free [NBP3-05651]](https://resources.bio-techne.com/images/products/MEK1-2-Antibody-Western-Blot-NBP3-05651-img0002.jpg "Western Blot: MEK1/2 AntibodyBSA Free [NBP3-05651]")
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
Potent, selective inhibitor of MEK1 and 2
| Chemical Name: | 1,4-Diamino-2,3-dicyano-1,4-bis[2-aminophenylthio]butadiene |
Potent inhibitor of MEK1/2
| Alternate Names: | PD325901 |
| Chemical Name: | N-[(2R)-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Purity: | ≥99% (HPLC) |
MEK inhibitor
| Chemical Name: | 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one |
| Purity: | ≥98% (HPLC) |
Selective inhibitor of MEK1 and MEK2; brain penetrant
| Chemical Name: | α-[Amino[(4-aminophenyl)thio]methylene]-2-(trifluoromethyl)benzeneacetonitrile |
| Purity: | ≥99% (HPLC) |
Selective inhibitor of MEK1/2
| Chemical Name: | N-(Cyclopropylmethoxy)-3,4,5-trifluoro-2-[(4-iodo-2-methylphenyl)amino]-benzamide |
| Purity: | ≥98% (HPLC) |
Potent MEK1 inhibitor. Also inhibits IκBα phosphorylation
| Alternate Names: | (-)-Arctigenin |
| Chemical Name: | (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone |
| Purity: | ≥98% (HPLC) |
Potent and selective MEK inhibitor; orally bioavailable
| Chemical Name: | N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide |
| Purity: | ≥98% (HPLC) |
Selective MEK inhibitor
| Alternate Names: | CI-1040 |
| Chemical Name: | 2-[(2-Chloro-4-iodophenyl)amino]-N-cyclopropylmethoxy)-3,4-difluorobenzamide |
| Purity: | ≥98% (HPLC) |
