Melanocortin-1 R/MC1R: ELISA Kits

Melanocortin-1 R/MC1R, the receptor for melanocyte-stimulating hormone (MSH), is a seven pass transmembrane G protein-coupled receptor that controls melanogenesis. Binding of MSH to MC1R activates the receptor and stimulates eumelanin synthesis. MC1R is a major determining factor in sun sensitivity and is a genetic risk factor for melanoma and non-melanoma skin cancer.