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NKp46/NCR1 Products

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

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173 results for "NKp46/NCR1" in Products

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173 results for "NKp46/NCR1" in Products

NKp46/NCR1 Products

NKp30/NCR3, NKp44/NCR2, and NKp46/NCR1 are termed natural cytotoxicity receptors (NCR). These receptors are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp44 is induced upon activation of resting NK cells with IL-2 and can bind to viral hemagglutinins. NK-mediated dendritic cell (DC) recognition is highly dependent on engagement of NKp30 and may result in lysis of the DC.

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Applications: WB, Flow, IHC, AgAct, CyTOF-reported, Dual ISH-IHC, ICC
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: WB, Flow, IHC, AgAct, CyTOF-ready
Reactivity: Mouse
Applications: WB, IHC, ICC
Reactivity: Human
Applications: WB
Reactivity: Mouse
Applications: Flow, CyTOF-reported
Reactivity: Mouse
Applications: Flow, AgAct
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: Flow
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: WB
Reactivity: Mouse
Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Mouse
Applications: IHC, WB, Flow, CyTOF-ready
Reactivity: Human, Mouse
Applications: Flow
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human

Clone 195314 was used by HLDA to establish CD designation

Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

Applications: Flow
Reactivity: Mouse
Applications: Flow
Reactivity: Human

Recombinant Monoclonal Antibody.

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