Other ER Stress/UPR Inhibitors Products
Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.
8 results for "Other ER Stress/UPR Inhibitors" in Products
8 results for "Other ER Stress/UPR Inhibitors" in Products
Other ER Stress/UPR Inhibitors Products
Endoplasmic reticulum (ER) stress happens when the protein synthesis requirements of the cell exceed the protein folding capacity of the ER. Improperly folded proteins accumulate in the ER. This triggers the unfolded protein response (UPR) to restore ER homeostasis.
Selective inhibitor of eIF2α dephosphorylation
| Chemical Name: | 3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide |
| Purity: | ≥99% |
p97 ATPase (VCP) inhibitor
| Chemical Name: | (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one |
| Purity: | ≥98% |
SKP2 (S-phase kinase-associated protein 2) inhibitor; upregulates p27 and arrests cell cycle in G1 phase
| Chemical Name: | N-(4-Butyl-2-methylphenyl)acetamide |
| Purity: | ≥98% |
Potent inhibitor of ER-associated protein degradation and translocation
| Chemical Name: | 3-(4-Chlorophenyl)-4-[[[(4-chlorophenyl)amino]carbonyl]hydroxyamino]-5,5-dimethyl-2-oxo-1-imidazolidineacetic acid 2-[3-(5-nitro-2-furanyl)-2-propen-1-ylidene]hydrazide |
| Purity: | ≥98% |
Potent and selective p97 ATPase (VCP) allosteric inhibitor
| Chemical Name: | 3-[3-(Cyclopentylthio)-5-[[[2-methyl-4'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]oxy]methyl]-4H-1,2,4-triazol-4-yl]pyridine |
| Purity: | ≥98% |
Dimeric Smac mimetic; potent IAP inhibitor
| Chemical Name: | 3,3'-[2,4-Hexadiyne-1,6-diylbis[oxy[(1S,2R)-2,3-dihydro-1H-indene-2,1-diyl]]]bis[N-methyl-L-alanyl-(2S)-2-cyclohexylglycyl-L-prolinamide |
| Purity: | ≥97% |
ATP-competitive inhibitor of p97 ATPase
| Chemical Name: | 2-(2-Amino-1H-benzimidazole-1-yl)-8-methoxy-N-(phenylmethyl)-4-quinazolinamine |
| Purity: | ≥99% |
Potent and selective ASK1 inhibitor; orally bioavailable
| Chemical Name: | 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide dihydrochloride |
| Purity: | ≥98% |
