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PAR2 Products

Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.

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158 results for "PAR2" in Products

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158 results for "PAR2" in Products

PAR2 Products

Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.

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Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: IHC
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: IHC, WB
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: Flow
Reactivity: Human
Applications: IHC, WB, ICC/IF, Flow
Reactivity: Human, Mouse, Rat

Recombinant Monoclonal Antibody

Applications: IHC, WB, ELISA, IP
Reactivity: Human, Mouse, Rat, Monkey
Applications: WB, ELISA, MA, AP
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: IHC
Reactivity: Human
Applications: ELISA, Flow, Func
Reactivity: Human

Recombinant Monoclonal Antibody

Applications: AC
Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: Flow, CyTOF-ready
Reactivity: Human
Applications: Flow, CyTOF-ready
Reactivity: Human
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