PAR2 Products
Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.
158 results for "PAR2" in Products
158 results for "PAR2" in Products
PAR2 Products
Protease-Activated Receptor 2 (PAR2) is a protease activated 7-transmembrane G-protein-coupled receptor. Human PAR2 contains a cleavage site for trypsin, mast cell tryptase or coagulation factor VIIa or Xa, 11 amino acids (aa) C-terminal to the signal sequence. Cleavage creates a tethered ligand that activates the 361 aa receptor. PAR2 is expressed in kidney, pancreas, stomach, intestine, airway, skin, bladder and brain; activation stimulates release of inflammatory and nociceptive mediators. PAR2 is downregulated by ubiquination, endocytosis and degradation. Mature human PAR2 shows 78% amino acid identity with mouse PAR2 over the extracellular portions.
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #9X8E6 |
Applications: | IHC, WB |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Reactivity: | Human |
Details: | Mouse IgG2a Monoclonal Clone #344222 |
Applications: | Flow |
Recombinant Monoclonal Antibody
Reactivity: | Human, Mouse, Rat |
Details: | Rabbit IgG Monoclonal Clone #SR1993 |
Applications: | IHC, WB, ICC/IF, Flow |
Reactivity: | Human, Mouse, Rat, Monkey |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC, WB, ELISA, IP |
Applications: | WB, ELISA, MA, AP |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG2 Monoclonal Clone #Amgen patent anti-PAR-2 |
Applications: | ELISA, Flow, Func |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #PAR650097 |
Applications: | ELISA, Flow, Func |
Reactivity: | Human |
Details: | Rabbit IgG Polyclonal |
Applications: | IHC |
Recombinant Monoclonal Antibody
Reactivity: | Human |
Details: | Human IgG1 Monoclonal Clone #Regeneron patent anti-PAR-2 |
Applications: | ELISA, Flow, Func |
Applications: | AC |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #344222 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #344222 |
Applications: | Flow, CyTOF-ready |
Reactivity: | Human |
Details: | Mouse IgG2A Monoclonal Clone #344222 |
Applications: | Flow, CyTOF-ready |