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PDGF-BB Products

PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.

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31 results for "PDGF-BB" in Products

31 results for "PDGF-BB" in Products

PDGF-BB Products

PDGF-BB (Platelet-Derived Growth Factor BB) is a homodimeric molecule expressed by hepatocytes and nonresorbing osteoclasts, and it promotes osteoblast development and bone formation. It is also produced by platelets, macrophages, and mast cells. At sites of injury, it promotes neutrophil and macrophage infiltration for debridement, fibroblast secretion of new extracellular matrix, and IGF-I-mediated re-epithelialization. The traditional receptor for PDGF is either a homodimer or heterodimer created from two type I transmembrane RTKs, PDGF R alpha and PDGF R beta. PDGF-BB has been shown to bind the alpha/alpha homodimer, alpha/beta heterodimer, and the beta/beta homodimer in vitro, and act through the beta/beta homodimer in vivo.

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Animal-Free

Applications: Simple Plex

Simple Plex Human PDGF-BB assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Contains 4 membranes - each spotted in duplicate with 105 different cytokine antibodies

Contains 4 membranes-each spotted in duplicate with 111 different cytokine antibodies

Contains 4 membranes - each spotted in duplicate with 55 different angiogenesis antibodies

Applications: Simple Plex
Applications: Ctrl, Simple Plex

Control for use with Human and Non-Human Primate PDGF-BB Simple Plex Cartridge Kit

Applications: WB, Neut
Reactivity: Human
Applications: WB
Reactivity: Human

Contains 4 membranes-each spotted in duplicate with 79 different cytokine antibodies

Applications: WB, Neut
Reactivity: Human
Applications: BA
Applications: BA

Intended for preclinical researchers who may transition to GMP PDGF-BB for their clinical work

Applications: Simple Plex

Simple Plex Non-Human Primate PDGF-BB assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.

Applications: BA
Applications: IHC, WB, ICC/IF
Reactivity: Human, Mouse, Rat
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