Pentraxin 3/TSG-14 Products
Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.
12 results for "Pentraxin 3/TSG-14" in Products
12 results for "Pentraxin 3/TSG-14" in Products
Pentraxin 3/TSG-14 Products
Pentraxin 3 (PTX3), also known as TNF-stimulated gene 14 (TSG-14), is a secreted glycoprotein belonging to the Pentraxin family of proteins. It is the prototypical long Pentraxin, exhibiting a C-terminal Pentraxin domain characteristic of the family, and a unique N-terminal domain. It is produced by several cell types including endothelial and mononuclear cells. PTX3 acts as a pattern recognition receptor with non-redundant roles in the innate immune response to several microbial agents including the fungal pathogen Aspergillus fumigatus. Overexpression leads to enhanced pro-inflammatory responses. PTX3 is induced in response to LPS and inflammatory cytokines including TNF-alpha and IL-1 beta.
| Sensitivity: | 0.02 ng/mL |
| Applications: | ELISA |
| Assay Range: | 0.23 - 15 ng/mL (Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma) |
| Assay Range: | 218 - 14,000 pg/mL |
| Applications: | ELISA |
| Source: | NS0 |
| Accession #: | P48759 |
| Applications: | Bind |
| Reactivity: | Human |
| Details: | Mouse IgG2a Monoclonal Clone #PPJ0069 |
| Applications: | WB, ELISA |
| Assay Range: | 218 - 14,000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2a Monoclonal Clone #265641 |
| Applications: | WB |
| Reactivity: | Mouse |
| Details: | Rat IgG2b Monoclonal Clone #265629 |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG2b Monoclonal Clone #247911 |
| Reactivity: | Mouse |
| Details: | Goat IgG Polyclonal |
| Applications: | WB |