PHLDA3: Proteins and Enzymes
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor
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3 results for "PHLDA3 Proteins and Enzymes" in Products
3 results for "PHLDA3 Proteins and Enzymes" in Products
PHLDA3: Proteins and Enzymes
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its directs transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May acts as a tumor suppressor
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| Applications: | WB, ELISA, MA, AP, PAGE |
![SDS-PAGE: Recombinant Human PHLDA3 GST (N-Term) Protein [H00023612-Q01]](https://resources.bio-techne.com/images/products/qc_test-H00023612-Q01-1.jpg "SDS-PAGE: Recombinant Human PHLDA3 GST (N-Term) Protein [H00023612-Q01]")
| Applications: | WB, ELISA, MA, AP |
| Applications: | AC |