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PIWIL1/HIWI: Proteins and Enzymes

PIWIL1 (piwi-like 1), also called HIWI (human homolog of drosophila piwi), is a cytoplasmic protein of the PIWI subgroup of the Argonaute family. PIWI domains bind a class of ~29-30 nucleotide RNAs termed piRNAs (piwi domain-binding RNAs). PIWIL1 orthologs are expressed with piRNAs in germ cells and are essential for spermatogenesis in mice. CD34+ hematopoietic progenitor cell PIWIL1 is downregulated upon differentiation. When overexpressed in leukemic cell lines, PIWIL1 inhibits growth and induces apoptosis.

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2 results for "PIWIL1/HIWI Proteins and Enzymes" in Products

2 results for "PIWIL1/HIWI Proteins and Enzymes" in Products

PIWIL1/HIWI: Proteins and Enzymes

PIWIL1 (piwi-like 1), also called HIWI (human homolog of drosophila piwi), is a cytoplasmic protein of the PIWI subgroup of the Argonaute family. PIWI domains bind a class of ~29-30 nucleotide RNAs termed piRNAs (piwi domain-binding RNAs). PIWIL1 orthologs are expressed with piRNAs in germ cells and are essential for spermatogenesis in mice. CD34+ hematopoietic progenitor cell PIWIL1 is downregulated upon differentiation. When overexpressed in leukemic cell lines, PIWIL1 inhibits growth and induces apoptosis.

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Applications: WB, ELISA, MA, AP
Applications: AC
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