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PKC iota/lambda/zeta Products

Atypical members of the Protein Kinase C (PKC) family of serine/threonine protein kinases include PKC iota/lambda and PKC zeta. Members of the atypical PKC subfamily are calcium-independent and do not require phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. They have been shown to serve as convergent downstream targets for the PI 3-kinase and TC10 signaling pathways and can regulate NF-kappa B activation during inflammation and cell survival signaling. Atypical PKCs are also implicated in insulin signaling and glucose regulation.

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1 result for "PKC iota/lambda/zeta" in Products

1 result for "PKC iota/lambda/zeta" in Products

PKC iota/lambda/zeta Products

Atypical members of the Protein Kinase C (PKC) family of serine/threonine protein kinases include PKC iota/lambda and PKC zeta. Members of the atypical PKC subfamily are calcium-independent and do not require phosphatidylserine, diacylglycerol (DAG), or exogenous phorbol esters for activation. They have been shown to serve as convergent downstream targets for the PI 3-kinase and TC10 signaling pathways and can regulate NF-kappa B activation during inflammation and cell survival signaling. Atypical PKCs are also implicated in insulin signaling and glucose regulation.

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Applications: WB, Simple Western, IHC
Reactivity: Human, Mouse, Rat
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