PREX2: Proteins and Enzymes

PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDPfor free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gammasubunits of heterotrimeric G

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PREX2 functions as a RAC1 guanine nucleotide exchange factor (GEF), activating Rac proteins by exchanging bound GDPfor free GTP. Its activity is synergistically activated by phosphatidylinositol-3,4,5-triphosphate and the beta gammasubunits of heterotrimeric G

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